PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18946018-5 2008 In cyclosporine A-treated renal transplant fibroblasts, azithromycin blocked the accumulation of total collagen in culture media and the increase in type I collagen mRNA level, but recovered the reduced MMP-2 mRNA level to the control. Azithromycin 56-68 matrix metallopeptidase 2 Homo sapiens 203-208 18946018-6 2008 These results suggest that azithromycin may improve CIGO by blocking cyclosporine A-induced cell proliferation and collagen synthesis, and by activating MMP-2 in gingival fibroblasts of persons with cyclosporine A-induced gingival overgrowth. Azithromycin 27-39 matrix metallopeptidase 2 Homo sapiens 153-158 18946018-4 2008 Azithromycin elevated the reduced metalloproteinase (MMP)-1 and MMP-2 activities in cyclosporine A-treated renal transplant fibroblasts and normal fibroblasts. Azithromycin 0-12 matrix metallopeptidase 2 Homo sapiens 64-69