PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21167148-8	2011	Gene expression analysis of the liver explained the increase of protoporphyrin IX by dietary Ge-132 as it enhanced (P<0.05) aminolevulinic acid synthase 1 (Alas1), a rate-limiting enzyme of heme synthesis, expression 1.8-fold, but decreased ferrochelatase (Fech) expression 0.6-fold (P<0.05).	protoporphyrin IX	64-81	5'-aminolevulinate synthase 1	Rattus norvegicus	127-157	
21167148-8	2011	Gene expression analysis of the liver explained the increase of protoporphyrin IX by dietary Ge-132 as it enhanced (P<0.05) aminolevulinic acid synthase 1 (Alas1), a rate-limiting enzyme of heme synthesis, expression 1.8-fold, but decreased ferrochelatase (Fech) expression 0.6-fold (P<0.05).	protoporphyrin IX	64-81	5'-aminolevulinate synthase 1	Rattus norvegicus	159-164	
10395986-2	1999	Inhibition of the activity of the key heme biosynthesis enzyme delta-ALAS was most pronounced and prolonged during the first hours after CoCl2 and CoCl2 plus propranolol injections; this was associated with accumulation of Co2+--protoporphyrin-containing products of hemolysis.	protoporphyrin IX	229-243	5'-aminolevulinate synthase 1	Rattus norvegicus	69-73	
9113083-10	1997	These findings indicate that markedly elevated levels of protoporphyrin and extremely low levels of heme in the Harderian gland are the results of both decreased expression of FeC and markedly increased expression of ALAS-N and HO-1.	protoporphyrin IX	57-71	5'-aminolevulinate synthase 1	Rattus norvegicus	217-223