PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4055798-5 1985 Taken together, these results suggest the hypothesis that some step(s) in the pathway of iron from extracellular transferrin to intracellular protoporphyrin limits the overall rate of heme synthesis in reticulocytes. protoporphyrin IX 142-156 transferrin Homo sapiens 113-124 6707842-5 1984 Cord free erythrocyte protoporphyrin was negatively correlated with maternal ferritin at 34 weeks gestation (p = 0.016) and at delivery (p = 0.014), and with transferrin saturation at delivery (p = 0.026). protoporphyrin IX 22-36 transferrin Homo sapiens 158-169 3978231-7 1985 This suggests that some step (or steps) in the pathway of iron from extracellular transferrin to protoporphyrin limits the overall rate of heme synthesis in reticulocytes. protoporphyrin IX 97-111 transferrin Homo sapiens 82-93 2415053-0 1985 The relationship between the percentage saturation of maternal and cord plasma transferrin and the maternal and cord blood free erythrocyte protoporphyrin:haem ratio. protoporphyrin IX 140-154 transferrin Homo sapiens 79-90 2415053-1 1985 The relationship between the percentage saturation of maternal and cord plasma transferrin and the maternal and cord blood free erythrocyte protoporphyrin:haem ratio were investigated in 49 healthy mothers following an uncomplicated pregnancy, and in their full term newborn infants. protoporphyrin IX 140-154 transferrin Homo sapiens 79-90 2415053-5 1985 The results obtained suggest that the free erythrocyte protoporphyrin:haem ratio of blood has a significant negative correlation with that of the percentage saturation of plasma transferrin of the sample. protoporphyrin IX 55-69 transferrin Homo sapiens 178-189 31544812-5 2019 When rabbit anti-bovine transferrin (Tf) antibodies were incubated with biotinylated PPIX, the binding of anti-Tf antibodies with apo-Tf was indirectly detected using ALP-labeled avidin, suggesting that even if the antibody is modified with PPIX, the antibody-antigen reaction occurs. protoporphyrin IX 72-89 transferrin Homo sapiens 24-35 6318930-0 1983 [Modulation of the expression of transferrin receptors by iron, hemin and protoporphyrin IX]. protoporphyrin IX 74-91 transferrin Homo sapiens 33-44 27627839-1 2016 In erythroid cells, more than 90% of transferrin-derived iron enters mitochondria where ferrochelatase inserts Fe2+ into protoporphyrin IX. protoporphyrin IX 121-138 transferrin Homo sapiens 37-48 28752174-3 2017 Protoporphyrin IX (PpIX), a clinically approved photodynamic therapy agent, was loaded into the shell layer of the TRF-coated UCNPs (UCNP@TRF nanoparticles), which can be efficiently taken up by cancer cells for photodynamic therapy. protoporphyrin IX 0-17 transferrin Homo sapiens 115-118 28752174-3 2017 Protoporphyrin IX (PpIX), a clinically approved photodynamic therapy agent, was loaded into the shell layer of the TRF-coated UCNPs (UCNP@TRF nanoparticles), which can be efficiently taken up by cancer cells for photodynamic therapy. protoporphyrin IX 0-17 transferrin Homo sapiens 138-141 28752174-3 2017 Protoporphyrin IX (PpIX), a clinically approved photodynamic therapy agent, was loaded into the shell layer of the TRF-coated UCNPs (UCNP@TRF nanoparticles), which can be efficiently taken up by cancer cells for photodynamic therapy. protoporphyrin IX 19-23 transferrin Homo sapiens 115-118 28752174-3 2017 Protoporphyrin IX (PpIX), a clinically approved photodynamic therapy agent, was loaded into the shell layer of the TRF-coated UCNPs (UCNP@TRF nanoparticles), which can be efficiently taken up by cancer cells for photodynamic therapy. protoporphyrin IX 19-23 transferrin Homo sapiens 138-141 28752174-5 2017 We also demonstrated that an external magnetic field could be used to increase the uptake of UCNP@TRF-PpIX nanoparticles by MDA-MB-231 and HeLa cancer cells, and hence result in an enhanced photodynamic therapy efficiency. protoporphyrin IX 102-106 transferrin Homo sapiens 98-101 22925987-5 2012 Our findings present clear-cut evidence for the alteration of interactions between HSA and TF in the presence of PPIX and changes in drug-binding to HSA and HSA-PPIX complex upon interaction with TF. protoporphyrin IX 113-117 transferrin Homo sapiens 91-93 24392106-8 2014 Zeta potential analysis showed that the presence of TF increased the positive charges of the HSA-PPIX system. protoporphyrin IX 97-101 transferrin Homo sapiens 52-54 9461300-0 1997 Regulation of expression of ferritin H-chain and transferrin receptor by protoporphyrin IX. protoporphyrin IX 73-90 transferrin Homo sapiens 49-60 17003376-7 2007 Erythrocyte PPIX levels strongly correlated with serum transferrin levels. protoporphyrin IX 12-16 transferrin Homo sapiens 55-66 9461300-1 1997 The effect of protoporphyrin IX (hemin without iron) on the expression of transferrin receptor and ferritin was investigated in Friend leukemia cells. protoporphyrin IX 14-31 transferrin Homo sapiens 74-85 9461300-2 1997 Cells treated with protoporphyrin IX exhibit enhanced transferrin-receptor expression and markedly reduced ferritin synthesis. protoporphyrin IX 19-36 transferrin Homo sapiens 54-65 9461300-9 1997 We conclude that translation of ferritin mRNA and degradation of transferrin-receptor mRNA are inhibited in intact tissue-culture cells by protoporphyrin IX through a mechanism similar to that exerted by iron chelation, thus involving depletion of the intracellular iron pool. protoporphyrin IX 139-156 transferrin Homo sapiens 65-76