PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19953630-5	2010	RESULTS: The PpIX synthesis and mRNA expression of CPO was much higher in the cells treated with ALA-hx than ALA.	protoporphyrin IX	13-17	coproporphyrinogen oxidase	Homo sapiens	51-54	
22246987-11	2012	Moreover, PpIX synthesis and expression levels of protoporphyrinogen oxidase (PPO) and coproporphyrinogen oxidase (CPO) were much higher in MCF-7/ADR cells than MCF-7 cells.	protoporphyrin IX	10-14	coproporphyrinogen oxidase	Homo sapiens	87-113	
27644131-7	2017	In addition, the expression of CPOX, an enzyme involved in PpIX synthesis, was evaluated.	protoporphyrin IX	59-63	coproporphyrinogen oxidase	Homo sapiens	31-35	
27644131-8	2017	mRNA levels of heme biosynthesis enzymes were analyzed, and PpIX fluorescence proved to correlate with the CPOX protein level, whereas no such correlation was observed at the mRNA level.	protoporphyrin IX	60-64	coproporphyrinogen oxidase	Homo sapiens	107-111	
19447864-7	2009	PpIX enhancement correlated with changes in protein expression of key porphyrin pathway enzymes, approximately 4-fold increase in coproporphyrinogen oxidase and stable or slightly decreased expression of ferrochelatase.	protoporphyrin IX	0-4	coproporphyrinogen oxidase	Homo sapiens	130-156	
10899392-4	2000	Rat and human liver coproporphyrinogen oxidase basal activities determined using this method were 0.41+/-0.05 nmol of protoporphyrin IX/h per mg of hepatic protein and 0.87+/-0.06 protoporphyrin IX/h per mg of hepatic protein, respectively.	protoporphyrin IX	118-135	coproporphyrinogen oxidase	Homo sapiens	20-46	
10899392-4	2000	Rat and human liver coproporphyrinogen oxidase basal activities determined using this method were 0.41+/-0.05 nmol of protoporphyrin IX/h per mg of hepatic protein and 0.87+/-0.06 protoporphyrin IX/h per mg of hepatic protein, respectively.	protoporphyrin IX	180-197	coproporphyrinogen oxidase	Homo sapiens	20-46	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	190-207	coproporphyrinogen oxidase	Homo sapiens	5-9	
7947969-6	1994	One heme group (protoporphyrin IX with an iron atom in the ferric state) is associated with one molecule of hCP.	protoporphyrin IX	16-33	coproporphyrinogen oxidase	Homo sapiens	108-111	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	254-271	coproporphyrinogen oxidase	Homo sapiens	5-9	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	254-271	coproporphyrinogen oxidase	Homo sapiens	14-18	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	254-271	coproporphyrinogen oxidase	Homo sapiens	14-18	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	190-207	coproporphyrinogen oxidase	Homo sapiens	14-18	
19339664-5	2009	Both CPOX and CPOX4 formed protoporphyrinogen-IX from coproporphyrinogen-III; however, the affinity of CPOX4 was twofold lower than that of CPOX (CPOX K(m) = 0.30 microM, V(max) = 0.52 pmol protoporphyrin-IX; CPOX4 K(m) = 0.54 microM, V(max) = 0.33 pmol protoporphyrin-IX).	protoporphyrin IX	190-207	coproporphyrinogen oxidase	Homo sapiens	14-18