PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24908960-3 2014 In patients with neutrophilic BA and deletion polymorphism of genes GSTT1 and GSTM1, there was a tendency to decreasing of the bronchial lability index through the decrease of bronchodilation, and bronchial response to histamine occurred to be higher than in children with the absence of polymorphism of the referred genes of the xenobiotics biotransformation system. Histamine 219-228 glutathione S-transferase mu 1 Homo sapiens 78-83 25790712-1 2014 INTRODUCTION: The relationship between bronchial hypersensitivity as the key phenomenon ofbronchial asthma and detoxication GSTM1 or GSTT1 gene polymorphism in children with neutrophilic phenotype of this disease remains unclear MATERIALS AND METHODS: 33 children with bronchial asthma of neutrophile phenotype were examined in histamine and dosed physical exercise (running) tests. Histamine 328-337 glutathione S-transferase mu 1 Homo sapiens 124-129 25790712-5 2014 CONCLUSION: Children with the neutrophilic phenotype of bronchial asthma having deletions in the GSTT1/GSTM1 system are characterized by bronchial hypersensitivity to histamine and dosed physical exercises. Histamine 167-176 glutathione S-transferase mu 1 Homo sapiens 103-108 14726165-8 2004 Compared with patients with a functional GSTM1 genotype, GSTM1 null patients had a significantly larger increase in IgE (median 102.5 U/mL [range 1.0-510.5] vs 45.5 U/mL [1.5-60.6], p=0.03) and histamine (14.0 nmol/L [-0.2-24.7] vs 7.4 nmol/L [1.2-12.3], p=0.02) after diesel exhaust particles plus allergen challenge. Histamine 194-203 glutathione S-transferase mu 1 Homo sapiens 57-62