PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21069571-5 2011 Effect of ketotifen fumarate was evaluated on A23187-elicited histamine release by RBL-2H3 cells. Histamine 62-71 RB transcriptional corepressor like 2 Rattus norvegicus 83-88 26935337-8 2016 Exposure of RBL-2H3 cells to CL-pAK compared with AK, resulted in lower levels of mast degranulation and histamine. Histamine 105-114 RB transcriptional corepressor like 2 Rattus norvegicus 12-17 23839821-8 2013 Thus, ELISA determination of the histamine release from RBL-2H3 cells is a suitable in vitro model to assay the anaphylactoid reaction of Xue-Sai-Tong injection. Histamine 33-42 RB transcriptional corepressor like 2 Rattus norvegicus 56-61 21715270-5 2011 In our study, aegeline inhibited the histamine release from RBL-2H3 cells induced by DNP(24)-BSA. Histamine 37-46 RB transcriptional corepressor like 2 Rattus norvegicus 60-65 2943732-5 1986 The antibodies activated both RBL-2H3 cells and normal rat mast cells for histamine release. Histamine 74-83 RB transcriptional corepressor like 2 Rattus norvegicus 30-35 2427579-1 1986 Antigen-induced stimulatory signals as well as histamine secretion from the RBL-2H3 cells were found to be highly temperature dependent. Histamine 47-56 RB transcriptional corepressor like 2 Rattus norvegicus 76-81 29728446-8 2018 TAS05567 inhibited BCR-dependent signal transduction in Ramos cells, FcgammaR-mediated tumor necrosis factor-alpha production in THP-1 cells, and FcepsilonR-mediated histamine release from RBL-2H3 cells. Histamine 166-175 RB transcriptional corepressor like 2 Rattus norvegicus 189-194 29116752-3 2017 In fact, the surface potential at the FET gate decreased owing to secretions such as histamine from the IgE-bound RBL-2H3 cells, which reacted with the allergen. Histamine 85-94 RB transcriptional corepressor like 2 Rattus norvegicus 114-119 27498772-10 2016 RESULTS: Pretreatment with quercetin (3, 10, 30 mumol/L) dose-dependently inhibited excessive histamine release from paclitaxel-stimulated RBL-2H3 cells in vitro, and quercetin administration significantly suppressed the high plasma histamine levels in paclitaxel-treated rats. Histamine 94-103 RB transcriptional corepressor like 2 Rattus norvegicus 139-144 23172359-11 2013 Inhibition of activation of RBL-2H3 cells was observed via decrease in histamine, intracellular Ca2+ concentration, and FcepsilonRI mRNA expression. Histamine 71-80 RB transcriptional corepressor like 2 Rattus norvegicus 28-33 15240993-4 2004 However, its metabolite hesperetin potently inhibited the histamine release from RBL-2H3 cells induced by IgE and the PCA reaction. Histamine 58-67 RB transcriptional corepressor like 2 Rattus norvegicus 81-86 29435881-0 2006 Ephedrae herba (Mao) decreased histamine content in RBL-2H3 cells. Histamine 31-40 RB transcriptional corepressor like 2 Rattus norvegicus 52-57 15465017-6 2004 We have moreover identified Munc13-4 as a Rab27A target using a CytoTrap system and found that exogenous expression of Munc13-4 affects antigen-induced histamine release from RBL-2H3 cells. Histamine 152-161 RB transcriptional corepressor like 2 Rattus norvegicus 175-180 15465017-7 2004 These results demonstrate that Rab27A plays a crucial role in antigen-induced histamine release from RBL-2H3 cells. Histamine 78-87 RB transcriptional corepressor like 2 Rattus norvegicus 101-106 17178388-4 2007 Three omega-6 PUFAs (AA, alpha-LN and LA) dose-dependently increased the cytosolic free-calcium concentration and histamine release from RBL-2H3 cells. Histamine 114-123 RB transcriptional corepressor like 2 Rattus norvegicus 137-142 15879676-4 2005 In vitro, PGD(2) suppressed the antigen-induced histamine release from RBL-2H3 cells, but PGE(2) and PGI(2) did not. Histamine 48-57 RB transcriptional corepressor like 2 Rattus norvegicus 71-76 12029497-11 2002 When RBL-2H3 cells were sensitized with the serum from mice injected with PAM extract, they released histamine in response to anti-IgE. Histamine 101-110 RB transcriptional corepressor like 2 Rattus norvegicus 5-10 12230104-4 2002 We found that the 40% ethanol extract of mangosteen inhibited IgE-mediated histamine release from RBL-2H3 cells with greater potency than the water extract of Rubus suavissimus that has been used as an anti-allergy crude drug in Japan. Histamine 75-84 RB transcriptional corepressor like 2 Rattus norvegicus 98-103 11728390-0 2001 Effects of nitric oxide and hydrogen peroxide on histamine release from RBL-2H3 cells. Histamine 49-58 RB transcriptional corepressor like 2 Rattus norvegicus 72-77 15100859-6 2002 We used differential measurement to observe the histamine released from RBL-2H3 cells when stimulated with dinitrophenylated bovine serum albumin (DNP-BSA) as an antigen. Histamine 48-57 RB transcriptional corepressor like 2 Rattus norvegicus 72-77 9637364-0 1998 Characterization of mastoparan-induced histamine release from RBL-2H3 cells. Histamine 39-48 RB transcriptional corepressor like 2 Rattus norvegicus 62-67 10924324-3 2000 EGCG inhibited histamine release from RBL-2H3 cells in response to antigen or the calcium-ionophore A23187, while (-)-epicatechin (EC) had little effect. Histamine 15-24 RB transcriptional corepressor like 2 Rattus norvegicus 38-43 10746164-0 1999 Constituents in watercress: inhibitors of histamine release from RBL-2H3 cells induced by antigen stimulation. Histamine 42-51 RB transcriptional corepressor like 2 Rattus norvegicus 65-70 11297859-0 2001 Screening of several Indonesian medicinal plants for their inhibitory effect on histamine release from RBL-2H3 cells. Histamine 80-89 RB transcriptional corepressor like 2 Rattus norvegicus 103-108 11297859-1 2001 Twelve alcoholic extracts and 12 hexane extracts of plant materials selected on the basis of medicinal folklore for asthma treatment in Indonesia were studied for their activity in inhibiting histamine release from RBL-2H3 cells (rat basophilic leukemia cell line), a tumor analog of mast cells. Histamine 192-201 RB transcriptional corepressor like 2 Rattus norvegicus 215-220 9720210-0 1998 Inhibitory effects of apple polyphenol on induced histamine release from RBL-2H3 cells and rat mast cells. Histamine 50-59 RB transcriptional corepressor like 2 Rattus norvegicus 73-78 9637364-1 1998 Mastoparan (5-30 microM), a tetradecapeptide isolated from wasp venom, caused histamine release from RBL-2H3 cells in a concentration- and time-dependent manner. Histamine 78-87 RB transcriptional corepressor like 2 Rattus norvegicus 101-106 8891756-4 1996 The elimination of PKC in RBL-2H3 cells induced significant suppression of histamine release, although the tyrosine phosphorylation of 78 and 92 kDa proteins was not inhibited. Histamine 75-84 RB transcriptional corepressor like 2 Rattus norvegicus 26-31 8768801-2 1996 OA inhibited IgE-mediated histamine release from RBL-2H3 cells and human basophils dose-dependently. Histamine 26-35 RB transcriptional corepressor like 2 Rattus norvegicus 49-54 7591368-2 1995 When RBL-2H3 cells are sensitized with IgE antibody and subsequently stimulated by an antigen, significant histamine release and the tyrosine phosphorylation of several proteins are observed. Histamine 107-116 RB transcriptional corepressor like 2 Rattus norvegicus 5-10 8906631-0 1996 Effects of fatty acids on accumulation and secretion of histamine in RBL-2H3 cells and leukotriene release from peritoneal exudate cells isolated from Wistar rats. Histamine 56-65 RB transcriptional corepressor like 2 Rattus norvegicus 69-74 8906631-2 1996 When RBL-2H3 cells were cultured for 24 h in the presence of 1 mM short chain fatty acids, a marked increase in histamine accumulation was observed, especially with butyric acid. Histamine 112-121 RB transcriptional corepressor like 2 Rattus norvegicus 5-10 7591368-4 1995 Preincubation for 10 min with 100 microM TEI-6472 caused significant inhibition of Fc epsilon RI-mediated histamine release from RBL-2H3 cells. Histamine 106-115 RB transcriptional corepressor like 2 Rattus norvegicus 129-134 7524478-0 1994 Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells. Histamine 57-66 RB transcriptional corepressor like 2 Rattus norvegicus 80-85 7523866-3 1994 Immune complexes formed with purified rat IgG and antigen as well as chemically cross-linked rat IgG induced histamine release from RBL-2H3 cells. Histamine 109-118 RB transcriptional corepressor like 2 Rattus norvegicus 132-137 7523866-5 1994 With chemically cross-linked rat IgG of each subclass, only IgG2a stimulated histamine release from RBL-2H3 cells and this release was also inhibited by prior saturation of the Fc epsilon RI with monomeric IgE. Histamine 77-86 RB transcriptional corepressor like 2 Rattus norvegicus 100-105 2141321-2 1990 After IgE receptor triggering with a specific antigen that was associated with histamine release, cytotoxic activity in the cell lysates and supernatants increased for 2 hr during the culture of RBL-2H3 cells. Histamine 79-88 RB transcriptional corepressor like 2 Rattus norvegicus 195-200 1699910-12 1990 CS-A also potently inhibited IgE-mediated histamine release from RBL-2H3 cells, without affecting their growth or viability. Histamine 42-51 RB transcriptional corepressor like 2 Rattus norvegicus 65-70 7532111-0 1994 PMA and calcium ionophore induce myosin and F-actin rearrangement during histamine secretion from RBL-2H3 cells. Histamine 73-82 RB transcriptional corepressor like 2 Rattus norvegicus 98-103 7509221-0 1994 Inhibition of histamine release from RBL-2H3 cells by protein synthesis inhibitors. Histamine 14-23 RB transcriptional corepressor like 2 Rattus norvegicus 37-42 7509221-1 1994 Effects of cycloheximide, an inhibitor of protein synthesis, on histamine release from RBL-2H3 cells were examined. Histamine 64-73 RB transcriptional corepressor like 2 Rattus norvegicus 87-92 1371921-4 1992 Wortmannin inhibited partially the A23187 induced histamine release from RBL-2H3 cells (40% inhibition at 1 microM). Histamine 50-59 RB transcriptional corepressor like 2 Rattus norvegicus 73-78 2162218-8 1990 These findings demonstrate that adenosine analogs have two distinct mechanisms on mediator release from RBL-2H3 cells; a stimulatory effect on both histamine and LT release, mediated via a pertussis-toxin-sensitive G protein and an inhibitory effect on LT release via a pertussis-toxin-insensitive pathway. Histamine 148-157 RB transcriptional corepressor like 2 Rattus norvegicus 104-109