PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20571831-3 2010 In the present study, we compared desacyl and acyl ghrelin with regard to acid secretion and histamine production in the rat stomach. Histamine 93-102 ghrelin and obestatin prepropeptide Rattus norvegicus 51-58 20691233-3 2010 In the present study, we investigated the roles of ghrelin and obestatin on mast cell degranulation and found that both ghrelin and obestatin induce the release of histamine from rat peritoneal mast cells. Histamine 164-173 ghrelin and obestatin prepropeptide Rattus norvegicus 51-58 20691233-3 2010 In the present study, we investigated the roles of ghrelin and obestatin on mast cell degranulation and found that both ghrelin and obestatin induce the release of histamine from rat peritoneal mast cells. Histamine 164-173 ghrelin and obestatin prepropeptide Rattus norvegicus 120-127 20691233-5 2010 Rat peritoneal mast cells and rat basophilic leukemia (RBL-2H3) cells did not express the ghrelin receptor GHSR1a, suggesting that histamine release induced by ghrelin occurs via a receptor-independent mechanism. Histamine 131-140 ghrelin and obestatin prepropeptide Rattus norvegicus 160-167 20571831-13 2010 CONCLUSIONS: The results indicate that acyl ghrelin stimulates gastric acid secretion via a mechanism involving activation of the vagus nerve and histamine release and synthesis and that desacyl ghrelin has no action on gastric acid secretion. Histamine 146-155 ghrelin and obestatin prepropeptide Rattus norvegicus 44-51 20571831-14 2010 Furthermore, the results demonstrate synergism between gastrin and acyl ghrelin in terms of gastric acid secretion via a mechanism involving histamine release and synthesis. Histamine 141-150 ghrelin and obestatin prepropeptide Rattus norvegicus 72-79 19009648-8 2008 However, we have shown that famotidine completely inhibited ghrelin-induced acid secretion and histidine decarboxylase (HDC) mRNA was increased in gastric mucosa by ghrelin injection which is inhibited by vagotomy Our results indicate that histamine is involved in the action of ghrelin on acid secretion. Histamine 240-249 ghrelin and obestatin prepropeptide Rattus norvegicus 165-172 19009648-4 2008 In the previous studies, the action of ghrelin on acid secretion was shown to be as strong as that of histamine and gastrin in in-vivo experiment. Histamine 102-111 ghrelin and obestatin prepropeptide Rattus norvegicus 39-46 19009648-8 2008 However, we have shown that famotidine completely inhibited ghrelin-induced acid secretion and histidine decarboxylase (HDC) mRNA was increased in gastric mucosa by ghrelin injection which is inhibited by vagotomy Our results indicate that histamine is involved in the action of ghrelin on acid secretion. Histamine 240-249 ghrelin and obestatin prepropeptide Rattus norvegicus 165-172 18611393-1 2008 Gastrin and ghrelin are secreted from G cells and X/A-like cells in the stomach, respectively, and respective hormones stimulate gastric acid secretion by acting through histamine and the vagus nerve. Histamine 170-179 ghrelin and obestatin prepropeptide Rattus norvegicus 12-19