PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30833108-0 2019 Discovery of novel 2,3-dihydro-1H-inden-1-amine derivatives as selective monoamine oxidase B inhibitors. 1-aminoindan 19-47 monoamine oxidase B Homo sapiens 73-92 30833108-2 2019 To find more potent and selective MAO-B inhibitors with novel chemical scaffold, we designed and synthesized a series of new 2,3-dihydro-1H-inden-1-amine derivatives on basis of our previous study. 1-aminoindan 125-153 monoamine oxidase B Homo sapiens 34-39 29339253-0 2018 Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline. 1-aminoindan 46-74 monoamine oxidase B Homo sapiens 117-136 15147504-1 2004 We have recently shown that the anti-Parkinson-propargyl-containing monoamine oxidase B (MAO-B) inhibitor drug, rasagiline [N-propargyl-(1R)-aminoindan], and its cholinesterase inhibitor derivatives TV3326 and TV3279, regulate amyloid precursor protein (APP) processing by a protein kinase C (PKC)-dependent mechanism in SH-SY5Y neuroblastoma and PC12 cells. 1-aminoindan 141-151 monoamine oxidase B Homo sapiens 68-87 16366596-8 2005 The crystal structure of N-methyl-1(R)-aminoindan bound to MAO B shows that its aminoindan ring adopts a different orientation compared to that of rasagiline. 1-aminoindan 39-49 monoamine oxidase B Homo sapiens 59-64