PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9820830-5	1998	Pretreatment of RMC with interleukin 1beta (IL-1beta), which up-regulated cyclo-oxygenase 2 and inducible nitric oxide synthase (NOS-2), significantly attenuated the conversion of [14C]prostaglandin H2 (PGH2) into the stable prostacyclin (PGI2) metabolite 6-oxo-prostaglandin F1alpha (6-oxo-PGF1alpha).	6-Ketoprostaglandin F1 alpha	256-283	interleukin 1 beta	Rattus norvegicus	25-42	
8418905-6	1993	Synthesis of prostacyclin was also stimulated by TNF alpha and IL-1 beta, as indicated by high levels of its stable metabolite 6-keto-prostaglandin F1 alpha.	6-Ketoprostaglandin F1 alpha	127-156	interleukin 1 beta	Rattus norvegicus	63-72	
16277686-4	2005	Levels of 6-keto-PGF1alpha and PGE2 peaked 24 hours after stimulation with IL-1beta; the induction of PGE2 was greater (11-fold versus 70-fold, respectively).	6-Ketoprostaglandin F1 alpha	10-26	interleukin 1 beta	Rattus norvegicus	75-83	
9820830-5	1998	Pretreatment of RMC with interleukin 1beta (IL-1beta), which up-regulated cyclo-oxygenase 2 and inducible nitric oxide synthase (NOS-2), significantly attenuated the conversion of [14C]prostaglandin H2 (PGH2) into the stable prostacyclin (PGI2) metabolite 6-oxo-prostaglandin F1alpha (6-oxo-PGF1alpha).	6-Ketoprostaglandin F1 alpha	256-283	interleukin 1 beta	Rattus norvegicus	44-52	
9820830-5	1998	Pretreatment of RMC with interleukin 1beta (IL-1beta), which up-regulated cyclo-oxygenase 2 and inducible nitric oxide synthase (NOS-2), significantly attenuated the conversion of [14C]prostaglandin H2 (PGH2) into the stable prostacyclin (PGI2) metabolite 6-oxo-prostaglandin F1alpha (6-oxo-PGF1alpha).	6-Ketoprostaglandin F1 alpha	285-300	interleukin 1 beta	Rattus norvegicus	25-42	
9820830-5	1998	Pretreatment of RMC with interleukin 1beta (IL-1beta), which up-regulated cyclo-oxygenase 2 and inducible nitric oxide synthase (NOS-2), significantly attenuated the conversion of [14C]prostaglandin H2 (PGH2) into the stable prostacyclin (PGI2) metabolite 6-oxo-prostaglandin F1alpha (6-oxo-PGF1alpha).	6-Ketoprostaglandin F1 alpha	285-300	interleukin 1 beta	Rattus norvegicus	44-52