PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19374865-9 2009 We also demonstrate for the first time that the COX-2 inhibitor rofecoxib can reduce 6-keto PGF1alpha production by both enzymatic inhibition and transcriptional repression. 6-Ketoprostaglandin F1 alpha 85-101 mitochondrially encoded cytochrome c oxidase II Homo sapiens 48-53 19040046-12 2008 In the cases with both COX-2 -765GG and PGIS CC genotypes, the serum 6-keto-PGF1alpha levels was lower than that of others (P < 0.05). 6-Ketoprostaglandin F1 alpha 69-85 mitochondrially encoded cytochrome c oxidase II Homo sapiens 23-28 19040046-14 2008 Populations with both COX-2 -765GG and PGIS CC genotypes were more at risk with MI than others which might be resulted from the decreased serum 6-keto-PGF1alpha concentration. 6-Ketoprostaglandin F1 alpha 144-160 mitochondrially encoded cytochrome c oxidase II Homo sapiens 22-27 17143555-10 2007 Diosgenin increased COX-2 activity resulting in PGE2 and 6-keto-PGF1alpha overproduction in human RA FLS. 6-Ketoprostaglandin F1 alpha 57-73 mitochondrially encoded cytochrome c oxidase II Homo sapiens 20-25 11926591-5 2002 The activity of COX-2 was assessed by measuring the production of 6-keto-prostaglandin F1alpha in the presence of exogenous arachidonic acids (10 microM, 10 min) by enzyme immunoassay. 6-Ketoprostaglandin F1 alpha 66-94 mitochondrially encoded cytochrome c oxidase II Homo sapiens 16-21 11950805-8 2002 Injured tissues treated with the selective COX-1 inhibitor SC-560 (5x10(-6) M) or the COX-2 inhibitor NS-398 (5x10(-6) M) recovered to control levels of resistance within three hours, associated with significant elevations of PGE and 6-keto-PGF1alpha compared with untreated tissues. 6-Ketoprostaglandin F1 alpha 234-250 mitochondrially encoded cytochrome c oxidase II Homo sapiens 86-91 12664572-0 2002 Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. 6-Ketoprostaglandin F1 alpha 49-66 mitochondrially encoded cytochrome c oxidase II Homo sapiens 12-17 32485532-4 2020 COX-2 inhibitory activity was further demonstrated by the inhibition of the accumulation of 6-keto-PGF1alpha, a metabolite of COX-2 products in two cancer cell lines. 6-Ketoprostaglandin F1 alpha 92-108 mitochondrially encoded cytochrome c oxidase II Homo sapiens 0-5 32485532-4 2020 COX-2 inhibitory activity was further demonstrated by the inhibition of the accumulation of 6-keto-PGF1alpha, a metabolite of COX-2 products in two cancer cell lines. 6-Ketoprostaglandin F1 alpha 92-108 mitochondrially encoded cytochrome c oxidase II Homo sapiens 126-131 29483877-10 2018 There is a decrease in the percentage of AA, associated with an increase of PLA2, COX2/TXA2R, CYP450 4A, and 5-LOX which leads to a greater synthesis of PGE2 than of 6-keto-PGF1alpha, thus contributing to the formation of the aortic aneurysm. 6-Ketoprostaglandin F1 alpha 166-182 mitochondrially encoded cytochrome c oxidase II Homo sapiens 82-86