PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29045468-0 2017 Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression. cordycepin 0-10 CASP8 and FADD like apoptosis regulator Homo sapiens 122-129 29844932-6 2018 In addition to activating caspases, we show that, cordycepin prevents TNF-alpha-induced increase in CCL5, Akt, NF-kappaB, and c-FLIPL activation and that CCL5 siRNA could inhibit Akt/NF-kappaB signaling. cordycepin 50-60 CASP8 and FADD like apoptosis regulator Homo sapiens 126-133 29045468-11 2017 Taken together, the results indicate that cordycepin inhibits TNF-alpha-mediated NF-kappaB/GADD45B signaling, which activates the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression, thus inducing TK-10 cell apoptosis. cordycepin 42-52 CASP8 and FADD like apoptosis regulator Homo sapiens 179-186 28035061-0 2017 Cordycepin induces autophagy-mediated c-FLIPL degradation and leads to apoptosis in human non-small cell lung cancer cells. cordycepin 0-10 CASP8 and FADD like apoptosis regulator Homo sapiens 38-45 28035061-9 2017 Therefore, we conclude that cordycepin induces apoptosis through autophagy-mediated downregulation of c-FLIPL in human NSCLC cells. cordycepin 28-38 CASP8 and FADD like apoptosis regulator Homo sapiens 102-109