PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30336060-14 2018 Furthermore, there was an apparent reduction in the expression levels of p-mTOR, p-p70S6K, matrix metalloproteinase (MMP)-2, and MMP-9 in the group treated with both cordycepin and TMZ, in comparison with those in the groups treated with either cordycepin or TMZ alone. cordycepin 166-176 mechanistic target of rapamycin kinase Homo sapiens 75-79 31242974-0 2019 Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway. cordycepin 0-10 mechanistic target of rapamycin kinase Homo sapiens 90-94 29735437-8 2018 CONCLUSION: Cordycepin inhibits the proliferation and induces apoptosis of HCT-116 cells through the mitochondrial pathway and induces autophagy via the AMPK/mTOR pathway. cordycepin 12-22 mechanistic target of rapamycin kinase Homo sapiens 158-162 19940154-9 2010 We conclude that many of the reported biological effects of cordycepin are likely to be due to its effects on mTOR and AMPK signaling. cordycepin 60-70 mechanistic target of rapamycin kinase Homo sapiens 110-114 28035061-6 2017 Meanwhile, cordycepin stimulated autophagy through suppressing mTOR signaling pathway in lung cancer cells. cordycepin 11-21 mechanistic target of rapamycin kinase Homo sapiens 63-67 27225448-8 2017 Furthermore, cordycepin suppressed the activation of extracellular signaling-regulated kinase (ERKs) and mammalian target of rapamycin (mTOR) in both PLC/PRF/5 and HepG2 cells. cordycepin 13-23 mechanistic target of rapamycin kinase Homo sapiens 105-134 27225448-8 2017 Furthermore, cordycepin suppressed the activation of extracellular signaling-regulated kinase (ERKs) and mammalian target of rapamycin (mTOR) in both PLC/PRF/5 and HepG2 cells. cordycepin 13-23 mechanistic target of rapamycin kinase Homo sapiens 136-140 34953496-14 2021 CONCLUSIONS: In brief, this study provides comprehensive evidence that cordycepin inhibits osteosarcoma cell growth and invasion and induces osteosarcoma cell apoptosis by activating AMPK and inhibiting the AKT/mTOR signaling pathway and enhances the sensitivity of osteosarcoma cells to cisplatin, suggesting that cordycepin is a promising treatment for osteosarcoma. cordycepin 71-81 mechanistic target of rapamycin kinase Homo sapiens 211-215