PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12441363-6 2002 Substantial increases in GR enzyme activity and mRNA levels were shown in keratinocytes and other human cell lines after exposure to low, subtoxic, micromolar concentrations of As(III) for 24 h. Upregulation of GSH synthesis paralleled the upregulation of GR as shown by increases in glutamate-cysteine lyase (GCL) enzyme activity and mRNA levels, cystine uptake, and intracellular GSH levels. as(iii) 177-184 glutamate-cysteine ligase catalytic subunit Homo sapiens 284-308 12441363-6 2002 Substantial increases in GR enzyme activity and mRNA levels were shown in keratinocytes and other human cell lines after exposure to low, subtoxic, micromolar concentrations of As(III) for 24 h. Upregulation of GSH synthesis paralleled the upregulation of GR as shown by increases in glutamate-cysteine lyase (GCL) enzyme activity and mRNA levels, cystine uptake, and intracellular GSH levels. as(iii) 177-184 glutamate-cysteine ligase catalytic subunit Homo sapiens 310-313