PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32415700-13	2020	Similarly, VPA-induced increase in acetylcholinesterase activity in the hippocampus and PFC were attenuated by post-natal treatment with metformin.	Valproic Acid	11-14	acetylcholinesterase	Rattus norvegicus	35-55	
32754946-6	2020	Reduced glutathione levels, paraoxanase, and acetylcholinesterase activities were significantly diminished in the VPA animals.	Valproic Acid	114-117	acetylcholinesterase	Rattus norvegicus	45-65	
30792162-7	2018	In addition, melatonin prevented VPA induced alterations in non-enzymatic antioxidant defence reduced glutathione (GSH) and activities of synaptosomal integral enzymes such as AChE, Na+, K+ -ATPase and MAO.	Valproic Acid	33-36	acetylcholinesterase	Rattus norvegicus	176-180	
25133713-4	2014	We found that prenatal exposure of valproic acid (VPA) induced dysregulation of cholinergic neuronal development, most notably the up-regulation of acetylcholinesterase (AChE) in the prefrontal cortex of affected rat and mouse offspring.	Valproic Acid	35-48	acetylcholinesterase	Rattus norvegicus	148-168	
25133713-4	2014	We found that prenatal exposure of valproic acid (VPA) induced dysregulation of cholinergic neuronal development, most notably the up-regulation of acetylcholinesterase (AChE) in the prefrontal cortex of affected rat and mouse offspring.	Valproic Acid	35-48	acetylcholinesterase	Rattus norvegicus	170-174	
25133713-4	2014	We found that prenatal exposure of valproic acid (VPA) induced dysregulation of cholinergic neuronal development, most notably the up-regulation of acetylcholinesterase (AChE) in the prefrontal cortex of affected rat and mouse offspring.	Valproic Acid	50-53	acetylcholinesterase	Rattus norvegicus	148-168	
25133713-4	2014	We found that prenatal exposure of valproic acid (VPA) induced dysregulation of cholinergic neuronal development, most notably the up-regulation of acetylcholinesterase (AChE) in the prefrontal cortex of affected rat and mouse offspring.	Valproic Acid	50-53	acetylcholinesterase	Rattus norvegicus	170-174	
23245536-7	2013	VPA, alone in prevention treatment, increased AChE activity in all brain regions evaluated; in the reversion, only in the prefrontal.	Valproic Acid	0-3	acetylcholinesterase	Rattus norvegicus	46-50	
23245536-1	2013	The present study aims to investigate the effects of mood stabilizers, lithium (Li) and valproate (VPA), on acetylcholinesterase (AChE) activity in the brains of rats subjected to an animal model of mania induced by D-amphetamine (D-AMPH).	Valproic Acid	88-97	acetylcholinesterase	Rattus norvegicus	108-128	
23245536-1	2013	The present study aims to investigate the effects of mood stabilizers, lithium (Li) and valproate (VPA), on acetylcholinesterase (AChE) activity in the brains of rats subjected to an animal model of mania induced by D-amphetamine (D-AMPH).	Valproic Acid	88-97	acetylcholinesterase	Rattus norvegicus	130-134	
23245536-1	2013	The present study aims to investigate the effects of mood stabilizers, lithium (Li) and valproate (VPA), on acetylcholinesterase (AChE) activity in the brains of rats subjected to an animal model of mania induced by D-amphetamine (D-AMPH).	Valproic Acid	99-102	acetylcholinesterase	Rattus norvegicus	108-128	
23245536-1	2013	The present study aims to investigate the effects of mood stabilizers, lithium (Li) and valproate (VPA), on acetylcholinesterase (AChE) activity in the brains of rats subjected to an animal model of mania induced by D-amphetamine (D-AMPH).	Valproic Acid	99-102	acetylcholinesterase	Rattus norvegicus	130-134