PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17156261-6	2007	High values of FSH, LH and FSH-to-LH ratio were common with carbamazepine while that of T and PRL were common in untreated patients and with valproate.	Valproic Acid	141-150	prolactin	Homo sapiens	94-97	
8038904-7	1994	The administration of naloxone did not modify, whereas sodium valproate significantly reduced the plasma GH and PRL rise during exercise.	Valproic Acid	55-71	prolactin	Homo sapiens	112-115	
12376268-7	2002	The basal PRL levels in patients with exclusive phenytion (PHT) or valproate (VPA), and in those with combined ministration of carbamazpine (CBZ+VPA+PHT), were significantly lower than the control levels (P<0.05).	Valproic Acid	67-76	prolactin	Homo sapiens	10-13	
12376268-7	2002	The basal PRL levels in patients with exclusive phenytion (PHT) or valproate (VPA), and in those with combined ministration of carbamazpine (CBZ+VPA+PHT), were significantly lower than the control levels (P<0.05).	Valproic Acid	78-81	prolactin	Homo sapiens	10-13	
8038904-8	1994	In the presence of sodium valproate, GH and PRL levels rose 3- and 1.5-fold, respectively, in response to exercise.	Valproic Acid	19-35	prolactin	Homo sapiens	44-47	
8038904-9	1994	When naloxone was given together with sodium valproate, both GH and PRL responses to exercise were abolished completely.	Valproic Acid	38-54	prolactin	Homo sapiens	68-71	
1525801-0	1992	Effect of sodium valproate on the secretion of prolactin, cortisol and growth hormone in migraine patients.	Valproic Acid	10-26	prolactin	Homo sapiens	47-56	
3012924-2	1986	A significant decrease of serum PRL concentrations was observed between 30 and 120 min after sodium valproate administration in both control and diabetic subjects.	Valproic Acid	93-109	prolactin	Homo sapiens	32-35	
3037356-0	1987	[Decrease of plasma prolactin in valproate therapy--expression of an increase in the activity of the central GABAergic system].	Valproic Acid	33-42	prolactin	Homo sapiens	20-29	
2506942-0	1989	Prolactin response to dopamine and valproate administration in breast cancer patients.	Valproic Acid	35-44	prolactin	Homo sapiens	0-9	
3148149-0	1988	Prolactin response to sodium valproate in schizophrenics with and without tardive dyskinesia.	Valproic Acid	22-38	prolactin	Homo sapiens	0-9	
3148149-3	1988	Sodium valproate decreased plasma prolactin levels in healthy subjects (P less than 0.001) and in schizophrenic patients with TD (P less than 0.001), but not in chronic schizophrenics without TD.	Valproic Acid	0-16	prolactin	Homo sapiens	34-43	
3148149-5	1988	Although the neural or biochemical substrate underlying the different responses of plasma prolactin to sodium valproate in schizophrenics with and without TD remains unclear, these results provide the first neuroendocrine evidence able to differentiate dyskinetic subjects from those without TD within a schizophrenic population.	Valproic Acid	103-119	prolactin	Homo sapiens	90-99	
3012924-4	1986	These data confirm the inhibitory control of the GABAergic system on PRL secretion in man as evidenced by the GABAergic drug sodium valproate.	Valproic Acid	125-141	prolactin	Homo sapiens	69-72	
23938015-3	2013	The bioactive testosterone/luteinizing hormone ratio and the prolactin level were significantly elevated in the VPA treatment group.	Valproic Acid	112-115	prolactin	Homo sapiens	61-70	
6799535-0	1982	The effects of the gabaergic drug, sodium valproate, on prolactin secretion in normal and hyperprolactinemic subjects.	Valproic Acid	35-51	prolactin	Homo sapiens	56-65	
6799535-2	1982	PRL circulating levels were measured by RIA in the samples obtained after acute oral treatment with 400 mg DPA.	Valproic Acid	107-110	prolactin	Homo sapiens	0-3	
6799535-4	1982	DPA treatment also lowered blood PRL levels in hyperprolactinemic subjects (seven females) without evidence of pituitary tumor.	Valproic Acid	0-3	prolactin	Homo sapiens	33-36	
3003777-0	1985	Failure of the GABAergic drug, sodium valproate, to reduce basal plasma prolactin secretion in chronic schizophrenia.	Valproic Acid	31-47	prolactin	Homo sapiens	72-81	
3003777-5	1985	Sodium valproate decreased PRL concentrations only in the healthy women.	Valproic Acid	0-16	prolactin	Homo sapiens	27-30	
6426828-0	1984	Effects of the GABAergic drug, sodium valproate, on the prolactin release evoked by pharmacological stimuli in normal women.	Valproic Acid	31-47	prolactin	Homo sapiens	56-65	
6426828-1	1984	Sodium valproate (DPA or Na-dipropylacetate), an anticonvulsant drug activating the endogenous GABAergic system, was administered orally at the dose of 400 mg to seventeen normal women 1 h before intravenous injections with three drugs which stimulate prolactin (PRL) release: TRH (200 micrograms bolus; six subjects); domperidone (5 mg bolus; six subjects); and sulpiride (5 mg bolus; five subjects).	Valproic Acid	0-16	prolactin	Homo sapiens	252-261	
6319114-4	1984	In epileptic men, all individual AEDs (except valproate) and AED polytherapy increased both basal and stimulated plasma levels of PRL.	Valproic Acid	46-55	prolactin	Homo sapiens	130-133	
6803821-0	1981	Effect of long-term treatment with sodium valproate on gonadotrophin and prolactin secretion in paediatric patients.	Valproic Acid	35-51	prolactin	Homo sapiens	73-82