PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29456722-10	2018	The results demonstrated that fucosterol significantly inhibited the expression levels of key proteins of the PI3K/Akt/mTOR signaling pathway.	fucosterol	30-40	AKT serine/threonine kinase 1	Homo sapiens	115-118	
29456722-0	2018	Fucosterol exhibits selective antitumor anticancer activity against HeLa human cervical cell line by inducing mitochondrial mediated apoptosis, cell cycle migration inhibition and downregulation of m-TOR/PI3K/Akt signalling pathway.	fucosterol	0-10	AKT serine/threonine kinase 1	Homo sapiens	209-212	
26395918-0	2015	Fucosterol protects cobalt chloride induced inflammation by the inhibition of hypoxia-inducible factor through PI3K/Akt pathway.	fucosterol	0-10	AKT serine/threonine kinase 1	Homo sapiens	116-119	
26395918-6	2015	In addition, fucosterol surpressed the phosphorylation of PI3K and Akt and accumulation of HIF1-alpha simulated by CoCl2.	fucosterol	13-23	AKT serine/threonine kinase 1	Homo sapiens	67-70	
26395918-7	2015	Taken together, these results suggested that fucosterol executed its protective effects against CoCl2 induced cytotoxicity and inflammation by the inhibition of hypoxia inducible factor through PI3K/Akt pathway.	fucosterol	45-55	AKT serine/threonine kinase 1	Homo sapiens	199-202	
27544192-6	2016	Moreover, fucosterol significantly reduced insulin-stimulated serine (Ser307) phosphorylation of insulin receptor substrate 1 (IRS1) and increased phosphorylation of Akt, phosphatidylinositol-3-kinase, and extracellular signal- regulated kinase 1 at concentrations of 12.5, 25, and 50 microM in insulin-resistant HepG2 cells.	fucosterol	10-20	AKT serine/threonine kinase 1	Homo sapiens	166-169