PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7881635-8 1994 However, the expression of IL-2 from TILs transduced with the IL-2 gene was downregulated after 2 to 3 weeks of G418 selection. antibiotic G 418 112-116 interleukin 2 Homo sapiens 27-31 10400988-4 1999 A number of G418-resistant transfectants were obtained and expression of IL-2 was determined. antibiotic G 418 12-16 interleukin 2 Homo sapiens 73-77 9573023-5 1998 Upon selection in the presence of increasing G418 concentrations, transduced NK cells were able to proliferate independently of IL-2 for more than 5 months and to secrete up to 5.5 ng/10(6) cells/24 h of IL-2. antibiotic G 418 45-49 interleukin 2 Homo sapiens 128-132 9573023-5 1998 Upon selection in the presence of increasing G418 concentrations, transduced NK cells were able to proliferate independently of IL-2 for more than 5 months and to secrete up to 5.5 ng/10(6) cells/24 h of IL-2. antibiotic G 418 45-49 interleukin 2 Homo sapiens 204-208 9458244-1 1998 We have demonstrated in previous studies that retrovirus-mediated transfer of the herpes simplex thymidine kinase (HS-tk) and neomycin phosphotransferase (neo) genes in CD3/IL-2 stimulated primary T lymphocytes followed by G418 selection resulted in T cells retaining both interleukin-2 (IL-2) and alloresponsiveness and specifically inhibited by ganciclovir (GCV). antibiotic G 418 223-227 interleukin 2 Homo sapiens 173-177 7881635-8 1994 However, the expression of IL-2 from TILs transduced with the IL-2 gene was downregulated after 2 to 3 weeks of G418 selection. antibiotic G 418 112-116 interleukin 2 Homo sapiens 62-66 1660837-5 1991 We tested this system by producing human interleukin-2 (IL-2) in L cells and Chinese hamster ovary (CHO) cells, and the results showed that high concentrations of G418 efficiently yielded L cell and CHO cell transfectants stably producing IL-2 at levels comparable with those previously attained using gene amplification. antibiotic G 418 163-167 interleukin 2 Homo sapiens 41-54 1660837-5 1991 We tested this system by producing human interleukin-2 (IL-2) in L cells and Chinese hamster ovary (CHO) cells, and the results showed that high concentrations of G418 efficiently yielded L cell and CHO cell transfectants stably producing IL-2 at levels comparable with those previously attained using gene amplification. antibiotic G 418 163-167 interleukin 2 Homo sapiens 56-60