PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12163380-10 2002 These lines up-regulate MUC2 expression in response to both methylation inhibition by 5-azacytidine and exposure to Pseudomonas aeruginosa lipopolysaccharide, both of whose effects can be suppressed by genistein pretreatment. Azacitidine 86-99 mucin 2, oligomeric mucus/gel-forming Homo sapiens 24-28 16721789-5 2006 To investigate the histone modification and DNA methylation of the promoter region of the MUC2 gene, we treated 2 human pancreatic cancer cell lines, PANC1 (MUC2-negative) and BxPC3 (MUC2-positive) with the DNA methyltransferase inhibitor 5-azacytidine (5-aza), the histone deacetylase inhibitor trichostatin A (TSA), and a combination of these agents. Azacitidine 239-252 mucin 2, oligomeric mucus/gel-forming Homo sapiens 90-94 16721789-5 2006 To investigate the histone modification and DNA methylation of the promoter region of the MUC2 gene, we treated 2 human pancreatic cancer cell lines, PANC1 (MUC2-negative) and BxPC3 (MUC2-positive) with the DNA methyltransferase inhibitor 5-azacytidine (5-aza), the histone deacetylase inhibitor trichostatin A (TSA), and a combination of these agents. Azacitidine 239-244 mucin 2, oligomeric mucus/gel-forming Homo sapiens 90-94 16721789-7 2006 The expression level of MUC2 mRNA in PANC1 cells exhibited a definite increase when treated with TSA and 5-aza/TSA, whereas 5-aza alone induced only a slight increase. Azacitidine 105-110 mucin 2, oligomeric mucus/gel-forming Homo sapiens 24-28