PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34939761-0	2021	Restoration of MiR-34a Expression by 5-Azacytidine Augments Alimta -Induced Cell Death in Non-Small Lung Cancer Cells by Downregulation of HMG B1, A2 and Bcl-2 Pathway.	Azacitidine	37-50	microRNA 34a	Homo sapiens	15-22	
34837933-8	2021	We found that treatment with 5-AZA could increase the expression of epigenetically silenced miRNAs, miR-34a, miR-34b and miR-124-1 in treated cells.	Azacitidine	29-34	microRNA 34a	Homo sapiens	100-107	
34939761-9	2021	Sequential exposure of the cells to 5-aza and Alimta enhanced miR-34a expression and significantly downregulated HMGB1, HMGA2 and BCL-2 expressions.	Azacitidine	36-41	microRNA 34a	Homo sapiens	62-69	
34939761-13	2021	Conclusion: 5-aza synergistically enhances Alimta induced apoptotic cell death through HMG proteins regulation, MIR34A gene expression and intrinsic apoptosis mechanism, providing a promising combination therapy in clinical lung cancer therapy.	Azacitidine	12-17	microRNA 34a	Homo sapiens	112-118	
34939761-2	2021	The aim of the present study was to investigate the combination effect of 5-Azacytidine (5-aza) and Alimta on the miR-34a and its target genes expression and induction of apoptotic cell death in non-small lung cancer A549 cells.	Azacitidine	74-87	microRNA 34a	Homo sapiens	114-121	
34939761-2	2021	The aim of the present study was to investigate the combination effect of 5-Azacytidine (5-aza) and Alimta on the miR-34a and its target genes expression and induction of apoptotic cell death in non-small lung cancer A549 cells.	Azacitidine	89-94	microRNA 34a	Homo sapiens	114-121	
27031715-9	2016	5-aza treatment caused an increase of miRNA-10b, -122, -200b levels in MCF-7/S cells, miRNA-34a, -10b, -122, -200b and -320a levels in MCF-7/Dox cells and miRNA-34a, -10b, -200b and -320a levels in MCF-7/DDP cells.	Azacitidine	0-5	microRNA 34a	Homo sapiens	86-95	
31781245-5	2019	5-Azacytidine (Aza-dC) repressed DNMT1 activation and upregulated miR-34a expression by promoter demethylation and suppressed the stemness of OSLCs in a dose-dependent manner.	Azacitidine	0-13	microRNA 34a	Homo sapiens	66-73	
26944831-9	2016	Subsequently, aberrant DNA methylation of the miR-34a promoter was found in human esophageal cancer, and 5-AZA-dC inhibited DNA methylation of the miR-34a promoter.	Azacitidine	105-110	microRNA 34a	Homo sapiens	147-154	
27031715-9	2016	5-aza treatment caused an increase of miRNA-10b, -122, -200b levels in MCF-7/S cells, miRNA-34a, -10b, -122, -200b and -320a levels in MCF-7/Dox cells and miRNA-34a, -10b, -200b and -320a levels in MCF-7/DDP cells.	Azacitidine	0-5	microRNA 34a	Homo sapiens	155-164	
22161761-2	2012	METHODS: Expression of the miR-34 family in synovial fibroblasts with or without stimulation with Toll-like receptor (TLR) ligands, tumor necrosis factor alpha (TNFalpha), interleukin-1beta (IL-1beta), hypoxia, or 5-azacytidine was analyzed by real-time polymerase chain reaction (PCR).	Azacitidine	214-227	microRNA 34a	Homo sapiens	27-33	
26499184-4	2016	Additionally, transfection of miR-34a mimics and demethylation by 5-azacytidine both resulted in the upregulation of miR-34a expression, which further induced declined cell proliferation and the enhanced apoptosis in PCa cells.	Azacitidine	66-79	microRNA 34a	Homo sapiens	117-124