PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23257429-7 2012 It is concluded that the inhibiton of NHE1 can significantly decrease the protein expression of Pgp in K562/DOX and K562/G01 cells, increase the accumulation of Rhodamine123 and doxorubicin in the cells of advanced patients and enhance the sensitivity of cells to imatinib in which the p38 MAPK signal transduction pathways involves. Rhodamine 123 161-173 solute carrier family 9 member A1 Homo sapiens 38-42 21576001-2 2011 As a result, after treatment with specific NHE1 inhibitor Cariporide or high K(+) buffer to decrease intracellular pH (pH(i)), cells from relapsed patients exhibited decreased Pgp level, enhanced Rhodamine123 and drug accumulation, decreased colony-forming ability and the modulations of mitogen-activated protein kinases (MAPKs) activities. Rhodamine 123 196-208 solute carrier family 9 member A1 Homo sapiens 43-47