PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14999727-1	2004	The purpose of this study was to assess the effect of mild heat and heat preconditioning on the uptake and permeability of a P-glycoprotein (P-gp) substrate, rhodamine 123 (R123), in a cell culture model of the blood-brain barrier (BBB).	Rhodamine 123	158-171	phosphoglycolate phosphatase	Bos taurus	125-139	
14999727-1	2004	The purpose of this study was to assess the effect of mild heat and heat preconditioning on the uptake and permeability of a P-glycoprotein (P-gp) substrate, rhodamine 123 (R123), in a cell culture model of the blood-brain barrier (BBB).	Rhodamine 123	158-171	phosphoglycolate phosphatase	Bos taurus	141-145	
10215691-7	1999	Both fentanyl (10 microM) and verapamil (100 microM) decreased release of rhodamine 123 from BBMECs, indicating that fentanyl is a substrate of P-gp in the BBMECs.	Rhodamine 123	74-87	phosphoglycolate phosphatase	Bos taurus	144-148	
12100750-2	2002	METHODS: Using rhodamine123 (Rh123) to examine the functional activity of P-gp in cultured bovine brain capillary endothelial cells (BCEC) and screen various principles on P-gp modulation in BBB.	Rhodamine 123	15-27	phosphoglycolate phosphatase	Bos taurus	74-78	
12100750-2	2002	METHODS: Using rhodamine123 (Rh123) to examine the functional activity of P-gp in cultured bovine brain capillary endothelial cells (BCEC) and screen various principles on P-gp modulation in BBB.	Rhodamine 123	15-27	phosphoglycolate phosphatase	Bos taurus	172-176	
12100750-2	2002	METHODS: Using rhodamine123 (Rh123) to examine the functional activity of P-gp in cultured bovine brain capillary endothelial cells (BCEC) and screen various principles on P-gp modulation in BBB.	Rhodamine 123	29-34	phosphoglycolate phosphatase	Bos taurus	74-78	
12100750-2	2002	METHODS: Using rhodamine123 (Rh123) to examine the functional activity of P-gp in cultured bovine brain capillary endothelial cells (BCEC) and screen various principles on P-gp modulation in BBB.	Rhodamine 123	29-34	phosphoglycolate phosphatase	Bos taurus	172-176	
10215691-6	1999	Release of [3H]fentanyl or rhodamine 123, a known substrate of P-gp, previously loaded in the BBMECs was studied in the presence or absence of either fentanyl or verapamil, a known competitive inhibitor of P-gp.	Rhodamine 123	27-40	phosphoglycolate phosphatase	Bos taurus	63-67	
8890933-0	1996	Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers.	Rhodamine 123	7-20	phosphoglycolate phosphatase	Bos taurus	59-73	
8890933-1	1996	The fluorescent dye, rhodamine 123, was used to evaluate the functional activity of the P-glycoprotein (P-gp) efflux transport system in primary cultured bovine brain microvessel endothelial cell (BBMEC) monolayers.	Rhodamine 123	21-34	phosphoglycolate phosphatase	Bos taurus	88-102	
8890933-1	1996	The fluorescent dye, rhodamine 123, was used to evaluate the functional activity of the P-glycoprotein (P-gp) efflux transport system in primary cultured bovine brain microvessel endothelial cell (BBMEC) monolayers.	Rhodamine 123	21-34	phosphoglycolate phosphatase	Bos taurus	104-108	
8890933-2	1996	Rhodamine 123 accumulation was increased significantly in BBMEC monolayers treated with the P-gp modifying agent, cyclosporin A (CSA).	Rhodamine 123	0-13	phosphoglycolate phosphatase	Bos taurus	92-96	
8890933-3	1996	Rhodamine 123 accumulation was also increased by other P-gp modifying agents.	Rhodamine 123	0-13	phosphoglycolate phosphatase	Bos taurus	55-59	
8890933-8	1996	Furthermore, these studies suggest that accumulation of rhodamine 123 in BBMEC monolayers can be used to quantitatively examine P-gp activity in the blood-brain barrier.	Rhodamine 123	56-69	phosphoglycolate phosphatase	Bos taurus	128-132