PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15749705-6	2005	To examine the requirements for resveratrol activation of SIRT1, we synthesized three p53 acetylpeptide substrates either lacking a fluorophore or containing a 7-amino-4-methylcoumarin (p53-AMC) or rhodamine 110 (p53-R110).	7-amino-4-methylcoumarin	190-193	tumor protein p53	Homo sapiens	186-189	
15749705-6	2005	To examine the requirements for resveratrol activation of SIRT1, we synthesized three p53 acetylpeptide substrates either lacking a fluorophore or containing a 7-amino-4-methylcoumarin (p53-AMC) or rhodamine 110 (p53-R110).	7-amino-4-methylcoumarin	190-193	tumor protein p53	Homo sapiens	186-189	
15749705-10	2005	Without resveratrol, the coumarin of p53-AMC peptide is solvent-exposed and makes no significant contacts with SIRT1.	7-amino-4-methylcoumarin	41-44	tumor protein p53	Homo sapiens	37-40