PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28000730-6 2016 Among several acridine derivatives examined, AIM4, which contains polar carboxyl groups in the side arms, significantly reduces TDP-43-YFP aggregation in the powerful yeast model cell and also abolishes in vitro amyloid-like aggregation of carboxyl terminal domain of TDP-43, as observed by AFM imaging. Acridines 14-22 Aim4p Saccharomyces cerevisiae S288C 45-49