PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16794561-0 2007 Blockade of 5-HT2a receptors reduces haloperidol-induced attenuation of reward. Haloperidol 37-48 5-hydroxytryptamine receptor 2A Rattus norvegicus 12-18 16220333-0 2005 ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Haloperidol 50-61 5-hydroxytryptamine receptor 2A Rattus norvegicus 11-17 12225700-0 2002 SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Haloperidol 58-69 5-hydroxytryptamine receptor 2A Rattus norvegicus 13-20 7516078-0 1994 In vivo dopamine-D2 and serotonin-5-HT2 receptor binding study of risperidone and haloperidol. Haloperidol 82-93 5-hydroxytryptamine receptor 2A Rattus norvegicus 24-48 10462131-2 1999 In the present study, in vivo receptor occupancy of 5-HT2A, alpha1, dopamine D2 and D3 receptors by NRA0045 was assessed, based on in vivo and ex vivo receptor binding, and findings were compared to reference antipsychotic drugs (haloperidol, risperidone, clozapine). Haloperidol 230-241 5-hydroxytryptamine receptor 2A Rattus norvegicus 52-58 9846274-5 1998 Drug occupation of 5-HT2A and dopamine D2 receptors in vivo examined with use of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) was 69.8% and 45.1%, respectively, after the acute administration of haloperidol (0.1 mg/kg) plus ritanserin (1 mg/kg). Haloperidol 204-215 5-hydroxytryptamine receptor 2A Rattus norvegicus 19-25 9379848-3 1997 Regionally, 32 days treatment with haloperidol (3 mg/kg/day), sulpiride (100 mg/kg/day) or clozapine (10 mg/kg/day) resulted in a drop of approximately 30-40% in 5HT2C mRNA levels in both cortex and cerebellum, and decreases (or non-significant trends) of 15-40% in 5HT2A mRNA levels in hippocampus, brainstem and mid brain. Haloperidol 35-46 5-hydroxytryptamine receptor 2A Rattus norvegicus 266-271 9181636-0 1997 8-OH-DPAT, a 5-HT1A agonist and ritanserin, a 5-HT2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release. Haloperidol 75-86 5-hydroxytryptamine receptor 2A Rattus norvegicus 46-52 9181636-1 1997 In this study, both catalepsy and changes in extracellular levels of striatal dopamine (DA) and dihydroxyphenyl acetic acid (DOPAC) induced by the typical neuroleptic haloperidol (HAL) were simultaneously assessed, using intracerebral microdialysis in freely moving rats, in the presence of either the 5-HT1A agonist 8-OH-DPAT or the 5-HT2A/C antagonist ritanserin. Haloperidol 167-178 5-hydroxytryptamine receptor 2A Rattus norvegicus 334-340 10646521-6 2000 Haloperidol-stimulated DA efflux (65-70%) was reduced by both SR 46349B (-32%) and the 5-HT2A/2B/2C antagonist ritanserin (-30%) but not affected by SB 206553. Haloperidol 0-11 5-hydroxytryptamine receptor 2A Rattus norvegicus 87-93 8935805-10 1996 In the second study, the direct acting 5-HT2A/2C receptor agonist/hallucinogen (+)1-4-iodo-2,5-dimethoxyphenyl-2-aminopropane (DOI) consistently disrupted auditory prepulse inhibition, and this effect was blocked by MDL 100,907 but not by haloperidol. Haloperidol 239-250 5-hydroxytryptamine receptor 2A Rattus norvegicus 39-45 7898773-4 1994 5-HT2A receptors: risperidone (9.07) > spiperone > chlorpromazine > clozapine > thioridazine = fluphenazine > haloperidol (6.03). Haloperidol 125-136 5-hydroxytryptamine receptor 2A Rattus norvegicus 0-6 8411785-0 1993 Time course of dopamine-D2 and serotonin-5-HT2 receptor occupancy rates by haloperidol and clozapine in vivo. Haloperidol 75-86 5-hydroxytryptamine receptor 2A Rattus norvegicus 31-55