PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15946544-3	2005	mRNA expressions of P-glycoprotein (MDR1), glutathione S-transferase Pi (GSTpi) and MDR-associated protein (MRP) of K562/Dox treated with Hal were assayed by RT-PCR.	Haloperidol	138-141	ATP binding cassette subfamily C member 1	Homo sapiens	108-111	
15946544-7	2005	After treatment with Hal 12.50 micromol/L, MDR1 and MRP mRNA expression were gradually down-regulated in a time-dependent manner on d1-d3, reducing to 76.3% and 64.6% of the control level on d3 (P < 0.05), while GSTpi mRNA expression decreased by 66.1% (P < 0.05) on d1-d2, and began to recover on d3.	Haloperidol	21-24	ATP binding cassette subfamily C member 1	Homo sapiens	52-55	
15946544-13	2005	CONCLUSION: A nontoxic concentration of haloperidol can significantly reverse drug resistance through a multi-pathway effect, including down-regulating mRNA expressions of MDR, GSTpi and MRP, inhibition of swelling-activated chloride channel and RVD in K562/Dox cells.	Haloperidol	40-51	ATP binding cassette subfamily C member 1	Homo sapiens	187-190