PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11799115-1 2002 Two distinct mannose 6-phosphate (Man-6-P) receptors (MPRs), the cation-dependent MPR (CD-MPR) and the insulin-like growth factor II/MPR (IGF-II/MPR), recognize a diverse population of Man-6-P-containing ligands. mannose-6-phosphate 13-32 mannose-6-phosphate receptor, cation dependent Homo sapiens 65-85 11799115-1 2002 Two distinct mannose 6-phosphate (Man-6-P) receptors (MPRs), the cation-dependent MPR (CD-MPR) and the insulin-like growth factor II/MPR (IGF-II/MPR), recognize a diverse population of Man-6-P-containing ligands. mannose-6-phosphate 13-32 mannose-6-phosphate receptor, cation dependent Homo sapiens 87-93 2544594-2 1989 The structural requirements for oligomerization and the generation of a functional mannose 6-phosphate (Man-6-P) binding site of the cation-dependent mannose 6-phosphate receptor (CD-MPR) were analyzed. mannose-6-phosphate 83-102 mannose-6-phosphate receptor, cation dependent Homo sapiens 133-178 10799489-1 2000 The two known mannose 6-phosphate receptors (MPR 46 and MPR 300) mediate the transport of mannose 6-phosphate-containing lysosomal proteins to lysosomes. mannose-6-phosphate 14-33 mannose-6-phosphate receptor, cation dependent Homo sapiens 45-51 8240300-4 1993 The results showed that the presence of a single oligosaccharide chain, particularly at position 87, on the CD-MPR significantly enhanced its mannose 6-phosphate (Man-6-P)-binding ability when compared with non-glycosylated receptors. mannose-6-phosphate 142-161 mannose-6-phosphate receptor, cation dependent Homo sapiens 108-114 1332979-5 1992 The recombinant intracellular and secreted enzyme forms were normally processed and phosphorylated; the secreted enzyme had mannose-6-phosphate moieties and bound the immobilized 215-kD mannose-6-phosphate receptor (M6PR). mannose-6-phosphate 124-143 mannose-6-phosphate receptor, cation dependent Homo sapiens 216-220 2170115-1 1990 BHK and mouse L cells transfected with the cDNA for the human 46 kd mannose 6-phosphate receptor (MPR 46) secrete excessive amounts of newly synthesized mannose 6-phosphate containing polypeptides. mannose-6-phosphate 68-87 mannose-6-phosphate receptor, cation dependent Homo sapiens 98-104 2544594-2 1989 The structural requirements for oligomerization and the generation of a functional mannose 6-phosphate (Man-6-P) binding site of the cation-dependent mannose 6-phosphate receptor (CD-MPR) were analyzed. mannose-6-phosphate 83-102 mannose-6-phosphate receptor, cation dependent Homo sapiens 180-186 32493818-3 2020 In Pompe cells, both the late autophagy pathway and the mannose-6-phosphate receptor (M6PR) pathway are interrupted. mannose-6-phosphate 56-75 mannose-6-phosphate receptor, cation dependent Homo sapiens 86-90 33946484-8 2021 All tumors expressed mannose-6-phosphate/insulin-like growth factor 2 receptor (M6PR/IGF2R). mannose-6-phosphate 21-40 mannose-6-phosphate receptor, cation dependent Homo sapiens 80-84 32027983-7 2020 In this study, a novel human M6PR (hM6PR)-overexpressing cell line originally established for hM6PR cellular uptake assay was utilized for production of hM6PR-ECD, and a novel small molecule biomimetic (aminophenyl-M6P) affinity resin was developed for the purification of M6PR-ECD. mannose-6-phosphate 29-32 mannose-6-phosphate receptor, cation dependent Homo sapiens 35-40 32027983-7 2020 In this study, a novel human M6PR (hM6PR)-overexpressing cell line originally established for hM6PR cellular uptake assay was utilized for production of hM6PR-ECD, and a novel small molecule biomimetic (aminophenyl-M6P) affinity resin was developed for the purification of M6PR-ECD. mannose-6-phosphate 29-32 mannose-6-phosphate receptor, cation dependent Homo sapiens 94-99 31591438-1 2019 Insulin-like growth factor II (IGF2) enhances memory in rodents via the mannose-6-phosphate receptor (M6PR), but the underlying mechanisms remain poorly understood. mannose-6-phosphate 72-91 mannose-6-phosphate receptor, cation dependent Homo sapiens 102-106 26503547-1 2016 The acquisition of mannose 6-phosphate (Man6P) on N-linked glycans of lysosomal enzymes is a structural requirement for their transport from the Golgi apparatus to lysosomes mediated by the mannose 6-phosphate receptors, 300 kDa cation-independent mannose 6-phosphate receptor (MPR300) and 46 kDa cation-dependent mannose 6-phosphate receptor (MPR46). mannose-6-phosphate 19-38 mannose-6-phosphate receptor, cation dependent Homo sapiens 297-342 26503547-1 2016 The acquisition of mannose 6-phosphate (Man6P) on N-linked glycans of lysosomal enzymes is a structural requirement for their transport from the Golgi apparatus to lysosomes mediated by the mannose 6-phosphate receptors, 300 kDa cation-independent mannose 6-phosphate receptor (MPR300) and 46 kDa cation-dependent mannose 6-phosphate receptor (MPR46). mannose-6-phosphate 19-38 mannose-6-phosphate receptor, cation dependent Homo sapiens 344-349 26503547-1 2016 The acquisition of mannose 6-phosphate (Man6P) on N-linked glycans of lysosomal enzymes is a structural requirement for their transport from the Golgi apparatus to lysosomes mediated by the mannose 6-phosphate receptors, 300 kDa cation-independent mannose 6-phosphate receptor (MPR300) and 46 kDa cation-dependent mannose 6-phosphate receptor (MPR46). mannose-6-phosphate 40-45 mannose-6-phosphate receptor, cation dependent Homo sapiens 297-342 26503547-1 2016 The acquisition of mannose 6-phosphate (Man6P) on N-linked glycans of lysosomal enzymes is a structural requirement for their transport from the Golgi apparatus to lysosomes mediated by the mannose 6-phosphate receptors, 300 kDa cation-independent mannose 6-phosphate receptor (MPR300) and 46 kDa cation-dependent mannose 6-phosphate receptor (MPR46). mannose-6-phosphate 40-45 mannose-6-phosphate receptor, cation dependent Homo sapiens 344-349 19928875-1 2010 The 46 kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) plays a key role in the delivery of lysosomal enzymes to the lysosome by binding newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and diverting them from the secretory pathway. mannose-6-phosphate 28-47 mannose-6-phosphate receptor, cation dependent Homo sapiens 58-64 16362416-8 2006 Like the mammalian MPR 46, zebrafish MPR 46 binds to the multimeric mannose-6-phosphate ligand phosphomannan and can rescue the missorting of lysosomal enzymes in mammalian MPR-deficient cells. mannose-6-phosphate 68-87 mannose-6-phosphate receptor, cation dependent Homo sapiens 19-25 18272523-1 2008 The cation-dependent mannose 6-phosphate receptor (CD-MPR) is a key component of the lysosomal enzyme targeting system that binds newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and transports them to endosomal compartments. mannose-6-phosphate 21-40 mannose-6-phosphate receptor, cation dependent Homo sapiens 51-57 15972892-1 2005 The 46 kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) plays an essential role in the biogenesis of lysosomes by diverting newly synthesized mannose 6-phosphate (Man-6-P)-containing lysosomal enzymes from the secretory pathway to acidified endosomes. mannose-6-phosphate 28-47 mannose-6-phosphate receptor, cation dependent Homo sapiens 58-64 15664992-1 2005 Biogenesis of lysosomes depends in mammalian cells on the specific recognition and targeting of mannose 6-phosphate-containing lysosomal enzymes by two mannose 6-phosphate receptors (MPR46, MPR300), key components of the extensively studied receptor-mediated lysosomal sorting system in complex metazoans. mannose-6-phosphate 96-115 mannose-6-phosphate receptor, cation dependent Homo sapiens 183-188