PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19195023-1	2009	The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) mediates biosynthetic sorting and endocytosis of various factors that impinge on the proliferation, migration and invasiveness of tumour cells.	mannose-6-phosphate	4-23	insulin-like growth factor 2 receptor	Mus musculus	64-73	
10945612-6	2000	Western blotting analysis revealed that SCC-VII cells are deficient in the 300 kDa mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R), a tumor suppressor with a central role in the intracellular transport of lysosomal enzymes.	mannose-6-phosphate	83-102	insulin-like growth factor 2 receptor	Mus musculus	143-152	
16179614-2	2005	In the present study, we report activation of TGF-beta by functional and physical co-operation of the mannose-6-phosphate/insulin-like-growth-factor-II receptor (CD222) and the urokinase-type plasminogen activator receptor (CD87).	mannose-6-phosphate	102-121	insulin-like growth factor 2 receptor	Mus musculus	162-167	
12729502-1	2003	Insulin-like growth factor II (IGF-II) and its receptor, the IGF-II/mannose-6-phosphate (IGF-II/M6P) receptor, are first expressed from the zygotic genome at the two-cell stage of mouse development.	mannose-6-phosphate	68-87	insulin-like growth factor 2 receptor	Mus musculus	89-109	
11311167-2	2001	Igf2r encodes a trans-membrane receptor that transports mannose-6-phosphate tagged proteins and insulin-like growth factor 2 to lysosomes.	mannose-6-phosphate	56-75	insulin-like growth factor 2 receptor	Mus musculus	0-5	
10884392-1	2000	The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF-II receptor) plays an important role in controlling the extracellular level of the insulin-like growth factor II (IGF-II) by mediating its binding at the cell surface and delivery to lysosomes.	mannose-6-phosphate	4-23	insulin-like growth factor 2 receptor	Mus musculus	68-83	
10993821-1	2000	The insulin-like growth factor-II/cation-independent mannose 6-phosphate (IGF-II/M6P) receptor transduces signals after binding IGF-II or M6P-bearing growth factors.	mannose-6-phosphate	53-72	insulin-like growth factor 2 receptor	Mus musculus	74-94	
9438420-5	1998	Because cellular activation of latent TGF-beta appears to require binding to the mannose-6-phosphate (M6P) binding site of the IGF-IIR and is plasmin and plasminogen activator dependent, the positive correlation of IGF-IIR levels and active TGF-beta2 levels seems to be key.	mannose-6-phosphate	81-100	insulin-like growth factor 2 receptor	Mus musculus	127-134	
10470859-1	1999	Both retinoids and the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) have been shown to play an important role in controlling cell growth during embryonic development and oncogenesis.	mannose-6-phosphate	23-42	insulin-like growth factor 2 receptor	Mus musculus	83-92	
9811861-1	1998	Previously, we showed that retinoic acid (RA) binds to the mannose-6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) with high affinity, suggesting that M6P/IGF2R may be a receptor for RA.	mannose-6-phosphate	59-78	insulin-like growth factor 2 receptor	Mus musculus	119-128	
9811861-1	1998	Previously, we showed that retinoic acid (RA) binds to the mannose-6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) with high affinity, suggesting that M6P/IGF2R may be a receptor for RA.	mannose-6-phosphate	59-78	insulin-like growth factor 2 receptor	Mus musculus	166-175	
9438420-5	1998	Because cellular activation of latent TGF-beta appears to require binding to the mannose-6-phosphate (M6P) binding site of the IGF-IIR and is plasmin and plasminogen activator dependent, the positive correlation of IGF-IIR levels and active TGF-beta2 levels seems to be key.	mannose-6-phosphate	102-105	insulin-like growth factor 2 receptor	Mus musculus	127-134	
33108069-4	2021	Here we show that insulin-like growth factor 2 (IGF-2) and mannose-6-phosphate (M6P), ligands of two independent binding sites of the cation-independent M6P/IGF-2 receptor (CIM6P/IGF-2R), reverse most major deficits of AS modeled in mice.	mannose-6-phosphate	59-78	insulin-like growth factor 2 receptor	Mus musculus	179-185	
8226743-2	1993	The cation-independent mannose 6-phosphate/insulin-like growth factor II receptor (CI-MPR) mediates intracellular sorting of lysosomal enzymes, binding lysosomal enzymes in the Golgi and delivering them to a lysosomal compartment.	mannose-6-phosphate	23-42	insulin-like growth factor 2 receptor	Mus musculus	83-89	
33505018-3	2021	Inceptor contains an extracellular cysteine-rich domain with similarities to INSR and IGF1R4, and a mannose 6-phosphate receptor domain that is also found in the IGF2 receptor (IGF2R)5.	mannose-6-phosphate	100-119	insulin-like growth factor 2 receptor	Mus musculus	177-182	
8062819-1	1994	In higher eukaryotes, the transport of soluble lysosomal enzymes involves the recognition of their mannose 6-phosphate signal by two receptors: the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor (CI-MPR) and the cation-dependent mannose 6-phosphate receptor (CD-MPR).	mannose-6-phosphate	99-118	insulin-like growth factor 2 receptor	Mus musculus	227-233	
23347038-0	2013	The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells.	mannose-6-phosphate	4-23	insulin-like growth factor 2 receptor	Mus musculus	41-50	
32369018-5	2020	Hippocampal or systemic administration of mannose-6-phosphate, like IGF2, significantly enhances memory retention and persistence in a CIM6P/IGF2R-dependent manner.	mannose-6-phosphate	42-61	insulin-like growth factor 2 receptor	Mus musculus	141-146	
23347038-1	2013	The M6P (mannose 6-phosphate)/IGF2R (insulin-like growth factor II receptor) interacts with a variety of factors that impinge on tumour invasion and metastasis.	mannose-6-phosphate	9-28	insulin-like growth factor 2 receptor	Mus musculus	37-75	
23468951-1	2013	The cation independent mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) functions in the transportation and regulation of insulin-like growth factor 2 (IGF2) and mannose 6-phosphate modified proteins.	mannose-6-phosphate	23-42	insulin-like growth factor 2 receptor	Mus musculus	82-87	
23468951-1	2013	The cation independent mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) functions in the transportation and regulation of insulin-like growth factor 2 (IGF2) and mannose 6-phosphate modified proteins.	mannose-6-phosphate	179-198	insulin-like growth factor 2 receptor	Mus musculus	82-87	
21081800-3	2010	Here, we studied the role of cathepsin B targeting during caerulein-induced pancreatitis in mouse mutants lacking the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor (CI-MPR) which normally mediates the trafficking of cathepsin B to lysosomes.	mannose-6-phosphate	137-156	insulin-like growth factor 2 receptor	Mus musculus	197-203