PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20363738-5 2010 281, 16084-16089) that establishes that L. donovani salvages purines primarily through hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and xanthine phosphoribosyltransferase (XPRT). Purines 61-68 xanthine phosphoribosyltransferase Leishmania donovani 146-180 16603734-6 2006 These data establish genetically that either HGPRT or XPRT is absolutely essential for purine acquisition, parasite viability, and parasite infectivity of mouse macrophages, that all exogenous purines are funneled to hypoxanthine and/or xanthine by L. donovani, and that the purine sources within the macrophage to which the parasites have access are HGPRT or XPRT substrates. Purines 193-200 xanthine phosphoribosyltransferase Leishmania donovani 360-364