PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31975428-5 2020 Interestingly, UHMK1-induced GC progression was mediated primarily via enhancing de novo purine synthesis because inhibiting purine synthesis reversed the effects of UHMK1 overexpression. Purines 89-95 U2AF homology motif kinase 1 Homo sapiens 15-20 31975428-5 2020 Interestingly, UHMK1-induced GC progression was mediated primarily via enhancing de novo purine synthesis because inhibiting purine synthesis reversed the effects of UHMK1 overexpression. Purines 125-131 U2AF homology motif kinase 1 Homo sapiens 15-20 31975428-11 2020 Collectively, these results show that the UHMK1-activated de novo purine synthesis pathway significantly promotes GC development. Purines 66-72 U2AF homology motif kinase 1 Homo sapiens 42-47