PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19646457-0 2009 Calcium-sensing receptor: a high-affinity presynaptic target for aminoglycoside-induced weakness. Aminoglycosides 65-79 calcium sensing receptor Homo sapiens 0-24 19646457-4 2009 We hypothesized that the presynaptic Ca(2+)-sensing receptor (CaSR) may contribute to aminoglycoside-induced weakness due to its role in modulating synaptic transmission and its sensitivity to aminoglycosides in heterologous expression systems. Aminoglycosides 86-100 calcium sensing receptor Homo sapiens 37-60 19646457-4 2009 We hypothesized that the presynaptic Ca(2+)-sensing receptor (CaSR) may contribute to aminoglycoside-induced weakness due to its role in modulating synaptic transmission and its sensitivity to aminoglycosides in heterologous expression systems. Aminoglycosides 86-100 calcium sensing receptor Homo sapiens 62-66 19646457-4 2009 We hypothesized that the presynaptic Ca(2+)-sensing receptor (CaSR) may contribute to aminoglycoside-induced weakness due to its role in modulating synaptic transmission and its sensitivity to aminoglycosides in heterologous expression systems. Aminoglycosides 193-208 calcium sensing receptor Homo sapiens 37-60 19646457-4 2009 We hypothesized that the presynaptic Ca(2+)-sensing receptor (CaSR) may contribute to aminoglycoside-induced weakness due to its role in modulating synaptic transmission and its sensitivity to aminoglycosides in heterologous expression systems. Aminoglycosides 193-208 calcium sensing receptor Homo sapiens 62-66 19646457-7 2009 Thus, at clinically relevant concentrations, aminoglycoside-induced weakness is likely precipitated by enhanced CaSR activation and subsequent decrease in terminal excitability rather than through direct inhibition of VACCs themselves. Aminoglycosides 45-59 calcium sensing receptor Homo sapiens 112-116 18261471-0 2008 Calcium-sensing receptor antagonism or lithium treatment ameliorates aminoglycoside-induced cell death in renal epithelial cells. Aminoglycosides 69-83 calcium sensing receptor Homo sapiens 0-24 15800129-0 2005 Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor. Aminoglycosides 0-15 calcium sensing receptor Homo sapiens 99-123