PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3906418-9	1985	In 21 of the 108 patients (19.4%) the beta 2m increased while the serum creatinine remained normal, suggesting an aminoglycoside nephrotoxicity which would have remained undetected if only serum creatinine had been measured.	Aminoglycosides	114-128	beta-2-microglobulin	Homo sapiens	38-45	
3906418-12	1985	Urinary beta 2m is more sensitive than serum creatinine and furthermore it allows one to differentiate aminoglycoside nephrotoxicity from functional renal failure.	Aminoglycosides	103-117	beta-2-microglobulin	Homo sapiens	8-15	
6370509-5	1984	beta 2-Microglobulin excretion can be used as a parameter for the relative binding affinity of aminoglycosides.	Aminoglycosides	95-110	beta-2-microglobulin	Homo sapiens	0-20	
7045782-5	1982	Meanwhile, accurate measurement of glomerular filtration and of beta 2-microglobulin urinary elimination seems clinically more useful for detection of impaired renal function than uneasy measurement of urinary enzyme excretion and than monitoring the aminoglycosides serum concentrations.	Aminoglycosides	251-266	beta-2-microglobulin	Homo sapiens	64-84	
84037-4	1978	Urinary beta2M is a non-specific indication of renal tubular damage, but heralds aminoglycoside-induced damage before standard tests of kidney function change.	Aminoglycosides	81-95	beta-2-microglobulin	Homo sapiens	8-14	
6164517-7	1981	Aminoglycosides (tobramycin, UK 18,892) lead to a cumulative increase of the renal excretion of beta 2-microglobulin and AAP while cephalosporins induce an increase of total proteins in the final urine under the same conditions.	Aminoglycosides	0-15	beta-2-microglobulin	Homo sapiens	96-116	
7011432-1	1980	Cytotoxic agents and aminoglycosides when given for a maximum of eleven days damaged the renal tubules as indicated by an increased urinary beta 2-microglobulin (beta 2-m), N-acetyl-beta-D-glucosaminidase (NAG) and total protein.	Aminoglycosides	21-36	beta-2-microglobulin	Homo sapiens	140-160	
6157048-0	1980	Patterns of urinary beta 2-microglobulin excretion by patients treated with aminoglycosides.	Aminoglycosides	76-91	beta-2-microglobulin	Homo sapiens	20-40	
6157048-3	1980	Our study of 52 aminoglycoside-treated patients included measurements of daily serum creatinine, daily 24-hour urinary beta 2-microglobulin (beta 2M) excretion, and determination of aminoglycoside tissue accumulation.	Aminoglycosides	16-30	beta-2-microglobulin	Homo sapiens	119-139	
6157048-3	1980	Our study of 52 aminoglycoside-treated patients included measurements of daily serum creatinine, daily 24-hour urinary beta 2-microglobulin (beta 2M) excretion, and determination of aminoglycoside tissue accumulation.	Aminoglycosides	16-30	beta-2-microglobulin	Homo sapiens	141-148	
95049-4	1979	The increase in urinary excretion of beta-2-microglobulin and retinol-binding-protein appeared only in patients treated with aminoglycoside and cephalosporin.	Aminoglycosides	125-139	beta-2-microglobulin	Homo sapiens	37-57	
84037-0	1978	Early detection of aminoglycoside nephrotoxicity with urinary beta-2-microglobulin.	Aminoglycosides	19-33	beta-2-microglobulin	Homo sapiens	62-82	
84037-1	1978	We used a radioimmunoassay to evaluate the changes in the urinary excretion of beta2-microglobulin (beta2M) in 21 patients receiving aminoglycosides for treatment of infection.	Aminoglycosides	133-148	beta-2-microglobulin	Homo sapiens	79-98	
84037-1	1978	We used a radioimmunoassay to evaluate the changes in the urinary excretion of beta2-microglobulin (beta2M) in 21 patients receiving aminoglycosides for treatment of infection.	Aminoglycosides	133-148	beta-2-microglobulin	Homo sapiens	100-106	
84037-3	1978	In six patients who developed aminoglycoside nephrotoxicity, urinary beta2M excretion rose 5 days or more before serum creatinine rose, and 5 of 6 nephrotoxic patients excreted more than 50 mg/day (normal, less than 0.1 mg/day).	Aminoglycosides	30-44	beta-2-microglobulin	Homo sapiens	69-75