PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17590326-4 2007 Four pesticides of carbaryl, malathion, dimethoate and monocrotophos were selected to discuss their inhibition efficiencies to AChE. Malathion 29-38 acetylcholinesterase (Cartwright blood group) Homo sapiens 127-131 18617161-1 2008 Organophosphorus pesticides (e.g. chlorpyrifos, malathion, and parathion) and nerve agents (sarin, tabun, and VX) are highly toxic organophosphorus compounds with strong inhibition potency against two key enzymes in the human body-acetylcholinesterase (AChE; EC 3.1.1.7) and butyrylcholinesterase (BuChE; EC 3.1.1.8). Malathion 48-57 acetylcholinesterase (Cartwright blood group) Homo sapiens 226-251 18617161-1 2008 Organophosphorus pesticides (e.g. chlorpyrifos, malathion, and parathion) and nerve agents (sarin, tabun, and VX) are highly toxic organophosphorus compounds with strong inhibition potency against two key enzymes in the human body-acetylcholinesterase (AChE; EC 3.1.1.7) and butyrylcholinesterase (BuChE; EC 3.1.1.8). Malathion 48-57 acetylcholinesterase (Cartwright blood group) Homo sapiens 253-257 18371787-6 2008 Under the optimal experimental conditions, the inhibition of malathion on AChE biosensor was proportional to its concentration in two ranges, from 0.001 to 0.1 microg mL(-1) and from 0.1 to 25 microg mL(-1), with detection limit of 0.001 microg mL(-1). Malathion 61-70 acetylcholinesterase (Cartwright blood group) Homo sapiens 74-78 15333628-8 2004 We conclude that short-term exposure to a single low dose of malathion causes prolonged modulation of the physiological function of the cutaneous vasculature and that this is, in part, through its action on acetylcholinesterase at both neuronal and nonneuronal sites. Malathion 61-70 acetylcholinesterase (Cartwright blood group) Homo sapiens 207-227 8806851-1 1996 The cholinergic toxicity of malathion is exacerbated by its isomerization product, isomalathion, which inhibits detoxifying carboxylesterases as well as target acetylcholinesterase (AChE). Malathion 28-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 160-180 10321902-4 1999 Bromine activation resulted in greater AChE inhibition than that produced by RLM activation for equivalent concentrations of fenitrothion, malathion, and EPN. Malathion 139-148 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-43 10321902-9 1999 AChE of hen brain homogenates was also more sensitive than homogenates from other species to malaoxon, the active form of malathion. Malathion 122-131 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 8806851-1 1996 The cholinergic toxicity of malathion is exacerbated by its isomerization product, isomalathion, which inhibits detoxifying carboxylesterases as well as target acetylcholinesterase (AChE). Malathion 28-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 182-186 33529929-6 2021 However, in the presence of AChE-inhibiting pesticides, such as fenobucarb and malathion, the activity of AChE is inhibited, and thus, the enzymatic hydrolysis of Myr cannot occur. Malathion 79-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 28-32 34319331-1 2021 Malathion is a commercially available insecticide that functions by acting as an acetylcholinesterase inhibitor. Malathion 0-9 acetylcholinesterase (Cartwright blood group) Homo sapiens 81-101 7927563-0 1994 Interaction of organophosphorus insecticides phosphamidon & malathion on lipid profile & acetylcholinesterase activity in human erythrocyte membrane. Malathion 64-73 acetylcholinesterase (Cartwright blood group) Homo sapiens 97-117 7927563-1 1994 The organophosphorus insecticides phosphamidon and malathion were found to inhibit the activity of human acetylcholinesterase in vitro, in the human erythrocyte membrane. Malathion 51-60 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-125 35583680-5 2022 In this study, the oxidation of malathion, parathion, and chlorpyrifos by n-bromosuccinimide (NBS) was investigated in an approach combining high-performance thin-layer chromatography (HPTLC) with an AChE-I assay. Malathion 32-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 200-204 35583680-10 2022 AChE-I effect recoveries in samples from a stormwater retention basin and receiving stream were between 69 and 92% for malathion, parathion, and chlorpyrifos. Malathion 119-128 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 35575998-1 2022 Malathion is a commercially available insecticide that functions by acting as an acetylcholinesterase inhibitor. Malathion 0-9 acetylcholinesterase (Cartwright blood group) Homo sapiens 81-101 33529929-6 2021 However, in the presence of AChE-inhibiting pesticides, such as fenobucarb and malathion, the activity of AChE is inhibited, and thus, the enzymatic hydrolysis of Myr cannot occur. Malathion 79-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 106-110 32698655-4 2020 Accordingly, organophosphate (malathion, acephate, chlorpyrifos methyl) and carbamate (carbofuran, methiocarb, methomyl), which are used to prevent harmful organisms in some agricultural products were enzymatically determined based on their inhibitory activity on AChE. Malathion 30-39 acetylcholinesterase (Cartwright blood group) Homo sapiens 264-268 33280706-0 2021 An ultra-sensitive and selective AChE based colorimetric detection of malathion using silver nanoparticle-graphene oxide (Ag-GO) nanocomposite. Malathion 70-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 33-37 33280706-1 2021 Herein, we propose rapid, precise acetylcholinesterase (AChE) inhibition-based sensing strategy for malathion detection in the presence of Ag-GO and acetylthiocholine (ATCh). Malathion 100-109 acetylcholinesterase (Cartwright blood group) Homo sapiens 34-54 33280706-1 2021 Herein, we propose rapid, precise acetylcholinesterase (AChE) inhibition-based sensing strategy for malathion detection in the presence of Ag-GO and acetylthiocholine (ATCh). Malathion 100-109 acetylcholinesterase (Cartwright blood group) Homo sapiens 56-60 33280706-5 2021 While the addition of malathion into the sensing system hindered the AChE activity and limited the TCh production, and thus inhibits the decrease in the SPR band intensity. Malathion 22-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 69-73 32721694-5 2020 In the present study, we determined whether the anti-AChE activity observed for chlorinated solutions of the organophosphorus insecticides malathion and methidathion could be solely attributed to the parent compounds and their oxons. Malathion 139-148 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-57 32721694-9 2020 For both the malathion-containing solution and the methidathion-containing solution, the calculated anti-AChE activities were almost the same as the observed activities at every chlorination time. Malathion 13-22 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-109 33560903-2 2021 Malathion (MT) is one of the most widely used organophosphorus insecticides which induces toxicity through oxidative stress induction, free radical production and acetylcholinesterase inhibition. Malathion 0-9 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-183 33560903-2 2021 Malathion (MT) is one of the most widely used organophosphorus insecticides which induces toxicity through oxidative stress induction, free radical production and acetylcholinesterase inhibition. Malathion 11-13 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-183 26979315-0 2016 Electrochemical detection of malathion pesticide using acetylcholinesterase biosensor based on glassy carbon electrode modified with conducting polymer film. Malathion 29-38 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-75 31575743-6 2019 These inhibitors, with high selectivity against human acetylcholinesterase and low to no toxicity in human cells and in mice, act synergistically with the OPs diazinon and malathion to reduce the amount of OP required to kill L. cuprina by up to 16-fold and abolish resistance. Malathion 172-181 acetylcholinesterase (Cartwright blood group) Homo sapiens 54-74 30558201-4 2018 The AChE/MHCS/GCE electrochemical sensor response exhibited two good linear ranges at the incubation time of 10 min at the Malathion concentration ranges of 0.01 to 100 ppb and 100 to 600 ppb, with a detection limit of 0.0148 ppb (S/N = 3). Malathion 123-132 acetylcholinesterase (Cartwright blood group) Homo sapiens 4-8 30558201-5 2018 The AChE/Fe3O4@MHCS/GCE electrochemical sensor that was operated with an incubation time of 12 min at the malathion concentration ranges between 0.01-50 ppb and 50-600 ppb had a detection limit of 0.0182 ppb (S/N = 3). Malathion 106-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 4-8 23202341-5 2013 Based on the inhibition of pesticides on the AChE activity, using malathion, chlorpyrifos, monocrotophos and carbofuran as model compounds, this biosensor showed a wide range, low detection limit, good reproducibility and high stability. Malathion 66-75 acetylcholinesterase (Cartwright blood group) Homo sapiens 45-49 24001830-0 2014 Acetylcholinesterase based biosensor for monitoring of Malathion and Acephate in food samples: a voltammetric study. Malathion 55-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 23819936-3 2013 After a deliberate ingestion of malathion, a 55-year-old male suffering from miosis, somnolence, bradycardia, muscular fasciculations, rales on auscultation, respiratory insufficiency, as well as from an inhibition of red blood cell acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BuChE), was admitted to hospital. Malathion 32-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 233-253 23819936-3 2013 After a deliberate ingestion of malathion, a 55-year-old male suffering from miosis, somnolence, bradycardia, muscular fasciculations, rales on auscultation, respiratory insufficiency, as well as from an inhibition of red blood cell acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BuChE), was admitted to hospital. Malathion 32-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 255-259 25461134-6 2015 Based on the inhibition of OPs on AChE activity, the sensor showed wide linear ranges of 7.98-2.00x10(3)pgmL(-1) and 4.3-1.00x10(3)pgmL(-1) with low detection limits of 4.14pgmL(-1) and 1.15pgmL(-1) for malathion and carbaryl, respectively. Malathion 203-212 acetylcholinesterase (Cartwright blood group) Homo sapiens 34-38 20472422-5 2010 Based on the inhibition of OPs on the AChE activity, using malathion as a model compound, the inhibition of malathion was proportional to its concentration ranging from 0.01 to 0.5 microg/mL and from 1 to 25 microg/mL, with a detection limit of 1.0 ng/mL. Malathion 59-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-42 20472422-5 2010 Based on the inhibition of OPs on the AChE activity, using malathion as a model compound, the inhibition of malathion was proportional to its concentration ranging from 0.01 to 0.5 microg/mL and from 1 to 25 microg/mL, with a detection limit of 1.0 ng/mL. Malathion 108-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-42