PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23504952-5 2013 Transferrin-TFR pathway blockers, such as NH4 Cl, CH3 NH2 , or trypsin, were added to the media and their effects were observed. Ammonium Chloride 42-48 transferrin Homo sapiens 0-11 23504952-8 2013 (2) The addition of blockers, either NH4 CL, CH3 NH2 , or trypsin, decreased the cellular transferrin-dependent IONP-PLL uptake, but not completely blocked the entry of IONP-PLL. Ammonium Chloride 37-43 transferrin Homo sapiens 90-101 8797088-6 1996 When the cytoplasmic pH was lowered by chasing cells that had been preincubated with 25 mM NH4Cl in an amiloride-containing Na(+)-free medium, more than 90% of internalization of Tfn in HT-1080 cells was inhibited, while that of HRP was reduced by only 35%. Ammonium Chloride 91-96 transferrin Homo sapiens 179-182 3622525-7 1987 Inhibitors of endocytic vesicle acidification (ammonium chloride and 2,4-dinitrophenol) inhibited iron unloading from endocytosed diferric transferrin, while microtubular inhibitors (colchicine and vindesine) and a microfilament inhibitor (cytochalasin B) reduced diferric transferrin uptake but had little effect on the iron unloading pathway. Ammonium Chloride 47-64 transferrin Homo sapiens 139-150 3622525-7 1987 Inhibitors of endocytic vesicle acidification (ammonium chloride and 2,4-dinitrophenol) inhibited iron unloading from endocytosed diferric transferrin, while microtubular inhibitors (colchicine and vindesine) and a microfilament inhibitor (cytochalasin B) reduced diferric transferrin uptake but had little effect on the iron unloading pathway. Ammonium Chloride 47-64 transferrin Homo sapiens 273-284 6465862-5 1984 The addition of either methylamine or ammonium chloride, both known blockers of transferrin-iron release through their lysosomotropic properties, inhibited total iron uptake. Ammonium Chloride 38-55 transferrin Homo sapiens 80-91 6576912-2 1983 NH4Cl and monensin, two agents which neutralize intracellular acidic compartments, block the segregation of iron from transferrin after endocytosis, while neither of these reagents affects internalization of diferric transferrin into the cell. Ammonium Chloride 0-5 transferrin Homo sapiens 118-129 6573263-4 1983 Chloroquine and NH4Cl, known as pH-raising agents in vesicles of the lysosomal system, inhibited iron accumulation and transferrin binding in a dose-dependent manner. Ammonium Chloride 16-21 transferrin Homo sapiens 119-130 1939162-6 1991 Compounds that interfere with transferrin receptor cycling and compartmentalization such as ammonium chloride decreased the cytotoxicity of transferrin-RNase. Ammonium Chloride 92-109 transferrin Homo sapiens 30-41 1939162-6 1991 Compounds that interfere with transferrin receptor cycling and compartmentalization such as ammonium chloride decreased the cytotoxicity of transferrin-RNase. Ammonium Chloride 92-109 transferrin Homo sapiens 140-151 1998959-17 1991 Ammonium chloride alters toxin cytotoxicity only when RTA is linked to TF, suggesting that only TF trafficks RTA through an acid-sensitive compartment prior to cytoplasmic translocation. Ammonium Chloride 0-17 transferrin Homo sapiens 71-73