PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17328821-9 2007 The LDLR of HepG2 cells incubated with conditioned medium was protected from PCSK9-mediated degradation by the addition of nocodazole or ammonium chloride, but was not protected when the conditioned medium was made hypertonic. Ammonium Chloride 137-154 low density lipoprotein receptor Homo sapiens 4-8 2303493-0 1990 Ammonium chloride causes reversible inhibition of low density lipoprotein receptor recycling and accelerates receptor degradation. Ammonium Chloride 0-17 low density lipoprotein receptor Homo sapiens 50-82 32188273-9 2020 Impairment of lysosome function (incubation with NH4Cl or knockdown of the lysosomal proteins LAMP1 or RAB7) abolished the effect of TMEM55B knockdown on LDLR in HepG2 cells. Ammonium Chloride 49-54 low density lipoprotein receptor Homo sapiens 154-158 15358785-6 2004 The LDLR levels are also reduced in stable HepG2 cells overexpressing NARC-1 or its natural mutant S127R, and this reduction is abrogated in the presence of 5 mm ammonium chloride, suggesting that overexpression of NARC-1 increases the turnover rate of the LDLR. Ammonium Chloride 162-179 low density lipoprotein receptor Homo sapiens 4-8