PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17272829-3 2007 Compared with hA-ITg mice, hA-ITg SR-BI-/- mice had a 4-fold higher total plasma cholesterol concentration, which occurred predominantly in 13-18 nm diameter HDL particles, a significant reduction in plasma esterified cholesterol-total cholesterol (EC/TC) ratio, and significantly lower plasma LCAT activity, suggesting a decrease in LCAT protein. ec 249-251 scavenger receptor class B member 1 Homo sapiens 34-39 17272829-6 2007 We conclude that the decreased EC/TC ratio in the plasma of hA-ITg SR-BI-/- mice is attributed to a reduction in LCAT reactivity with SM-enriched HDL particles. ec 31-33 scavenger receptor class B member 1 Homo sapiens 67-72