PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3680198-1	1987	Calmodulin antagonists, including phenothiazine, sulfonamide, butyrophenone, and imidazolium derivatives, were in vitro inhibitors of pea mitochondrial pyruvate dehydrogenase complex activity.	Sulfonamides	49-60	calmodulin 1	Homo sapiens	0-10	
2557928-0	1989	Inhibitory effects of newly synthesized sulfonamide derivatives on calmodulin-dependent phosphodiesterase activity and their modulation of the external ATP-dependent permeability change in mammalian cultured cells.	Sulfonamides	40-51	calmodulin 1	Homo sapiens	67-77	
2557928-3	1989	We have synthesized several new sulfonamide derivatives, which were found to inhibit calmodulin-dependent phosphodiesterase.	Sulfonamides	32-43	calmodulin 1	Homo sapiens	85-95	
7823773-5	1995	A calmodulin inhibitor, N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide (W-7), at the concentration of 10(-6) M and a myosin light-chain kinase inhibitor, 1-(5-chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine (ML-9), at concentrations above 10(-7) M also significantly blocked 10 mM nicotine-induced pepsinogen secretion.	Sulfonamides	64-75	calmodulin 1	Homo sapiens	2-12	
2427907-5	1986	A sulfonamide derivative, the compound N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) (2.5 X 10(-5)-2 X 10(-4) M), which selectively binds to CaM, inhibited the release of histamine from basophils.	Sulfonamides	2-13	calmodulin 1	Homo sapiens	166-169	
6502522-7	1984	A sulfonamide derivative, W-7, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (10(-5)-2 X 10(-4) M), which selectively binds to CaM, inhibited the release of lysosomal enzymes from PMNs.	Sulfonamides	2-13	calmodulin 1	Homo sapiens	146-149	
6120173-3	1981	Fc-mediated phagocytosis was also depressed by W-7, a sulfonamide derivative that inhibits the activity of Ca2+-calmodulin.	Sulfonamides	54-65	calmodulin 1	Homo sapiens	112-122	
6192958-2	1983	We have investigated the possibility that calmodulin plays a role in immediate hypersensitivity reactions by evaluating the effects of two agents, trifluoperazine dihydrochloride (TFP) and the sulfonamide derivative N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) which selectively bind to calmodulin.	Sulfonamides	193-204	calmodulin 1	Homo sapiens	42-52	
1847628-3	1991	Calmodulin antagonists including phenothiazine and sulfonamide derivatives significantly increased proteoglycanase activity and decreased collagenase activity.	Sulfonamides	51-62	calmodulin 1	Homo sapiens	0-10