PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7534104-3	1995	Several studies indicate that cytochrome P450-dependent metabolites of sulphonamides act as the nominal allergens.	Sulfonamides	71-84	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	30-45	
28080030-1	2017	Cytochrome P450 enzymes have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these reactions have been limited by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrate to a sulfonamide.	Sulfonamides	259-270	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15	
3203057-15	1988	Although the competitive inhibition between some sulphonamides and tolbutamide is consistent with metabolism by the same isozyme of cytochrome P-450 it does not prove it and further studies with purified enzymes will be necessary to confirm this.	Sulfonamides	49-62	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	132-148