PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8064808-9 1994 At 1 mg/kg po in rats, 18 and 92 (L-162,234) produced 85-87% peak inhibition of the AII pressor response with duration exceeding 6 h. The identification of triazolinone-based sulfonamide derivatives combining high AT1 affinity, considerably enhanced AT2 potency, and favorable in vivo properties provides insights relevant to the design of dual AT1/AT2 receptor antagonists. Sulfonamides 175-186 angiotensinogen Rattus norvegicus 84-87