PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19515557-0	2009	Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.	Sulfonamides	75-87	dipeptidyl peptidase 4	Homo sapiens	133-156	
20737212-7	2011	The contour plots of molecular fields resulting from these studies have suggested: (i) steric restriction with small electron rich substituent at 2- and 3-position of pyrrolidine ring, (ii) presence of electropositive ring linker between the pyrrolidine head and aryl tail, (iii) presence of electron-rich groups around the aryl tail moiety, and (iv) presence of sulfonamide between the ring linker and aryl tail which would increase DPP-IV binding affinity of the compounds.	Sulfonamides	363-374	dipeptidyl peptidase 4	Homo sapiens	434-440	
30243239-0	2018	Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies.	Sulfonamides	46-57	dipeptidyl peptidase 4	Homo sapiens	99-104	
32971414-3	2020	The sulfonamide-containing series (compounds 10-18) selectively inhibited alpha-glucosidase over DPP-4, in which compound 18 demonstrated the highest activity with an IC50 value of 5.69 +- 0.5 microM through a competitive inhibition mechanism.	Sulfonamides	4-15	dipeptidyl peptidase 4	Homo sapiens	97-102