PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15993055-3	2005	SAR trends were elucidated for sulfonamide derivatives with generality across different scaffolds.	Sulfonamides	31-42	sarcosine dehydrogenase	Homo sapiens	0-3	
26463131-3	2015	The results of the SAR developed highlight the relationship between the sulfonamide and quinoline nitrogen, while also suggesting that an aryl substituent at the 5-position of the quinoline ring contributes to the potency in the interaction assay.	Sulfonamides	72-83	sarcosine dehydrogenase	Homo sapiens	19-22	
22506561-3	2012	The SAR for steroid inhibition of G6PD has been substantially developed; the 3beta-alcohol can be replaced with 3beta-H-bond donors such as sulfamide, sulfonamide, urea, and carbamate.	Sulfonamides	151-162	sarcosine dehydrogenase	Homo sapiens	4-7	
18816537-6	2008	SAR for aromatase inhibition shows that compounds containing an alkylene- and thioether-based linker system are more potent than those that are ether-, sulfone-, or sulfonamide-based, and that the length of the linker has a limited effect on aromatase inhibition beyond two methylene units.	Sulfonamides	165-176	sarcosine dehydrogenase	Homo sapiens	0-3	
12941345-2	2003	A study of the SAR around sulfonamide 31 (IC(50)=5 nM, EC(50)=1400 nM) is discussed.	Sulfonamides	26-37	sarcosine dehydrogenase	Homo sapiens	15-18	
20493690-2	2010	Extensive SAR shows that a large number of sulfonamides at position 7 of the tricycle are very well tolerated.	Sulfonamides	43-55	sarcosine dehydrogenase	Homo sapiens	10-13	
18554753-0	2009	Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity.	Sulfonamides	44-55	sarcosine dehydrogenase	Homo sapiens	37-40