PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15080939-2	2004	The combination of a biphenylsulfonamide group with oxyamino oxygen in the pharmacophoric central skeleton of sulfonamide-based MMPi obtained in the new sulfonamides 10 seems to be able to give selectivity for MMP-2 over MMP-1.	Sulfonamides	29-40	matrix metallopeptidase 2	Homo sapiens	210-215	
15601584-0	2004	Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method.	Sulfonamides	23-34	matrix metallopeptidase 2	Homo sapiens	51-77	
15080939-2	2004	The combination of a biphenylsulfonamide group with oxyamino oxygen in the pharmacophoric central skeleton of sulfonamide-based MMPi obtained in the new sulfonamides 10 seems to be able to give selectivity for MMP-2 over MMP-1.	Sulfonamides	153-165	matrix metallopeptidase 2	Homo sapiens	210-215	
35489270-0	2022	Targeting the interplay between MMP-2, CA II and VEGFR-2 via new sulfonamide-tethered isomeric triazole hybrids; Microwave-assisted synthesis, computational studies and evaluation.	Sulfonamides	65-76	matrix metallopeptidase 2	Homo sapiens	32-37	
35489270-8	2022	Herein, we report concomitant inhibition of MMP-2, CA II, and VEGFR-2 via rationally designed 1,2,3- and 1,2,4-triazole hybrids bearing various sulfonamide appendages following pharmacophore hybridization strategy.	Sulfonamides	144-155	matrix metallopeptidase 2	Homo sapiens	44-49	
16875829-4	2006	The sulfonamide based IDA derivatives studied (compounds B1-B3) showed to be potent (nM range) against deep S1" pocket MMPs enzymes (i.e., MMP-2).	Sulfonamides	4-15	matrix metallopeptidase 2	Homo sapiens	119-123	
26346367-0	2015	Sulfonamide derivatives containing dihydropyrazole moieties selectively and potently inhibit MMP-2/MMP-9: Design, synthesis, inhibitory activity and 3D-QSAR analysis.	Sulfonamides	0-11	matrix metallopeptidase 2	Homo sapiens	93-98	
26346367-1	2015	New series of sulfonamide derivatives containing a dihydropyrazole moieties inhibitors of MMP-2/MMP-9 were discovered using structure-based drug design.	Sulfonamides	14-25	matrix metallopeptidase 2	Homo sapiens	90-95	
22411188-2	2012	Adapting findings from the literature of Zn(II) ion sensors, we previously reported chelating sulfonamide inhibitors of MMP-2, some of which showed excellent selectivity over other gelatinases (MMP-9).	Sulfonamides	94-105	matrix metallopeptidase 2	Homo sapiens	120-125	
16875829-4	2006	The sulfonamide based IDA derivatives studied (compounds B1-B3) showed to be potent (nM range) against deep S1" pocket MMPs enzymes (i.e., MMP-2).	Sulfonamides	4-15	matrix metallopeptidase 2	Homo sapiens	139-144