PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20626862-0	2010	Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells.	beta-Glucans	23-34	C-X-C motif chemokine ligand 8	Homo sapiens	77-81	
21796149-3	2011	beta-Glucan stimulation significantly increased IL-8, IL-6, and IL-1alpha production by NHEKs.	beta-Glucans	0-11	C-X-C motif chemokine ligand 8	Homo sapiens	48-52	
21796149-10	2011	Treatment with the ERK inhibitor PD98059 and with the p38 kinase inhibitor SB203580 effectively suppressed beta-glucan-induced IL-8 production by NHEKs.	beta-Glucans	107-118	C-X-C motif chemokine ligand 8	Homo sapiens	127-131	
20626862-3	2010	Several previous studies indicate that airway epithelial cells release the neutrophil chemoattractant proteins, MIP-2 (rodents) and IL-8 (humans), in response to Pneumocystis and purified Pneumocystis cell wall beta-glucans (PCBG) through the NF-kappaB-dependent pathway.	beta-Glucans	211-223	C-X-C motif chemokine ligand 8	Homo sapiens	132-136	
12433059-5	2002	However, beta-glucan itself induced the production of significant amounts of IL-8 and TF.	beta-Glucans	9-20	C-X-C motif chemokine ligand 8	Homo sapiens	77-88	
17230585-5	2007	As compared to placebo fecal water, beta-glucan enriched fecal water significantly increased IL-8 production in HT29 (5.0%; p = 0.046) and INT407 cells (22.0%; p = 0.028).	beta-Glucans	36-47	C-X-C motif chemokine ligand 8	Homo sapiens	93-97	
17895603-7	2007	Furthermore, a mAb to the beta-glucan receptor, Dectin-1, significantly (P<0.05) blocked the Sophy beta-glucan induced DNA synthesis in the PBMCs, and Sophy beta-glucan-induced production of IL-8 in the U937 cells.	beta-Glucans	26-37	C-X-C motif chemokine ligand 8	Homo sapiens	194-198	
17895603-8	2007	The Sophy beta-glucan-induced production of IL-8 in the U937 cells was significantly (P<0.01) blocked by the conventional protein kinase C (PKC) inhibitor Go6976, the novel PKC inhibitor Rottlerin, the protein kinase A (PKA) inhibitor H-89, and the protein tyrosine kinase (PTK) inhibitor herbimycin A.	beta-Glucans	10-21	C-X-C motif chemokine ligand 8	Homo sapiens	44-48	
17895603-10	2007	Studies employing reverse transcriptase-polymerase chain reaction (RT-PCR) showed that Sophy beta-glucan stimulated the expression of IL-8 mRNA in the U937 cells, and that this induction was inhibited by Rottlerin.	beta-Glucans	93-104	C-X-C motif chemokine ligand 8	Homo sapiens	134-138	
15300205-9	2004	RESULTS: beta-glucan significantly enhanced chemotaxis toward C5a and suppressed that toward IL-8 in a CR3-dependent fashion.	beta-Glucans	9-20	C-X-C motif chemokine ligand 8	Homo sapiens	93-97	
15300205-10	2004	In the competing chemotactic gradient assays (C5a vs IL-8), beta-glucan further enhanced migration toward C5a while not affecting that toward IL-8.	beta-Glucans	60-71	C-X-C motif chemokine ligand 8	Homo sapiens	53-57	
15300205-11	2004	CONCLUSIONS: beta-glucan selectively upregulates PMN chemotaxis toward C5a while suppressing chemotaxis toward IL-8.	beta-Glucans	13-24	C-X-C motif chemokine ligand 8	Homo sapiens	111-115	
25251945-6	2014	The beta-glucan-consisting glycans curdlan and zymosan stimulated IL-8 and CCL2 secretion by IEC lines.	beta-Glucans	4-15	C-X-C motif chemokine ligand 8	Homo sapiens	66-70	
11824547-0	2002	Synergistic action of beta-glucan and platelets on interleukin-8 production by human peripheral blood leukocytes.	beta-Glucans	22-33	C-X-C motif chemokine ligand 8	Homo sapiens	51-64	
10457157-7	1999	Co-incubation of MSG with mannan or beta-glucan decreased IL-8 release by 48% and 42% respectively, suggesting that MSG stimulates A549 cells in part through carbohydrate moieties.	beta-Glucans	36-47	C-X-C motif chemokine ligand 8	Homo sapiens	58-62	
24418375-3	2014	beta-glucan attenuated CD86 and CD80 expression and simultaneously reduced secretion of the inflammatory cytokines IL-2, IL-8, IL-12, TNF-alpha and IFN-gamma.	beta-Glucans	0-11	C-X-C motif chemokine ligand 8	Homo sapiens	121-125	
24418375-6	2014	In experiments with monocytes derived from healthy donors, beta-glucan inhibited IL-8, IL-12 and TNF-alpha production.	beta-Glucans	59-70	C-X-C motif chemokine ligand 8	Homo sapiens	81-85