PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17230585-5 2007 As compared to placebo fecal water, beta-glucan enriched fecal water significantly increased IL-8 production in HT29 (5.0%; p = 0.046) and INT407 cells (22.0%; p = 0.028). beta-Glucans 36-47 C-X-C motif chemokine ligand 8 Homo sapiens 93-97 24418375-3 2014 beta-glucan attenuated CD86 and CD80 expression and simultaneously reduced secretion of the inflammatory cytokines IL-2, IL-8, IL-12, TNF-alpha and IFN-gamma. beta-Glucans 0-11 C-X-C motif chemokine ligand 8 Homo sapiens 121-125 24418375-6 2014 In experiments with monocytes derived from healthy donors, beta-glucan inhibited IL-8, IL-12 and TNF-alpha production. beta-Glucans 59-70 C-X-C motif chemokine ligand 8 Homo sapiens 81-85 25251945-6 2014 The beta-glucan-consisting glycans curdlan and zymosan stimulated IL-8 and CCL2 secretion by IEC lines. beta-Glucans 4-15 C-X-C motif chemokine ligand 8 Homo sapiens 66-70 21796149-3 2011 beta-Glucan stimulation significantly increased IL-8, IL-6, and IL-1alpha production by NHEKs. beta-Glucans 0-11 C-X-C motif chemokine ligand 8 Homo sapiens 48-52 21796149-10 2011 Treatment with the ERK inhibitor PD98059 and with the p38 kinase inhibitor SB203580 effectively suppressed beta-glucan-induced IL-8 production by NHEKs. beta-Glucans 107-118 C-X-C motif chemokine ligand 8 Homo sapiens 127-131 20626862-0 2010 Pneumocystis cell wall beta-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells. beta-Glucans 23-34 C-X-C motif chemokine ligand 8 Homo sapiens 77-81 20626862-3 2010 Several previous studies indicate that airway epithelial cells release the neutrophil chemoattractant proteins, MIP-2 (rodents) and IL-8 (humans), in response to Pneumocystis and purified Pneumocystis cell wall beta-glucans (PCBG) through the NF-kappaB-dependent pathway. beta-Glucans 211-223 C-X-C motif chemokine ligand 8 Homo sapiens 132-136 17895603-7 2007 Furthermore, a mAb to the beta-glucan receptor, Dectin-1, significantly (P<0.05) blocked the Sophy beta-glucan induced DNA synthesis in the PBMCs, and Sophy beta-glucan-induced production of IL-8 in the U937 cells. beta-Glucans 26-37 C-X-C motif chemokine ligand 8 Homo sapiens 194-198 17895603-8 2007 The Sophy beta-glucan-induced production of IL-8 in the U937 cells was significantly (P<0.01) blocked by the conventional protein kinase C (PKC) inhibitor Go6976, the novel PKC inhibitor Rottlerin, the protein kinase A (PKA) inhibitor H-89, and the protein tyrosine kinase (PTK) inhibitor herbimycin A. beta-Glucans 10-21 C-X-C motif chemokine ligand 8 Homo sapiens 44-48 17895603-10 2007 Studies employing reverse transcriptase-polymerase chain reaction (RT-PCR) showed that Sophy beta-glucan stimulated the expression of IL-8 mRNA in the U937 cells, and that this induction was inhibited by Rottlerin. beta-Glucans 93-104 C-X-C motif chemokine ligand 8 Homo sapiens 134-138 10457157-7 1999 Co-incubation of MSG with mannan or beta-glucan decreased IL-8 release by 48% and 42% respectively, suggesting that MSG stimulates A549 cells in part through carbohydrate moieties. beta-Glucans 36-47 C-X-C motif chemokine ligand 8 Homo sapiens 58-62 15300205-9 2004 RESULTS: beta-glucan significantly enhanced chemotaxis toward C5a and suppressed that toward IL-8 in a CR3-dependent fashion. beta-Glucans 9-20 C-X-C motif chemokine ligand 8 Homo sapiens 93-97 15300205-10 2004 In the competing chemotactic gradient assays (C5a vs IL-8), beta-glucan further enhanced migration toward C5a while not affecting that toward IL-8. beta-Glucans 60-71 C-X-C motif chemokine ligand 8 Homo sapiens 53-57 15300205-11 2004 CONCLUSIONS: beta-glucan selectively upregulates PMN chemotaxis toward C5a while suppressing chemotaxis toward IL-8. beta-Glucans 13-24 C-X-C motif chemokine ligand 8 Homo sapiens 111-115 12433059-5 2002 However, beta-glucan itself induced the production of significant amounts of IL-8 and TF. beta-Glucans 9-20 C-X-C motif chemokine ligand 8 Homo sapiens 77-88 11824547-0 2002 Synergistic action of beta-glucan and platelets on interleukin-8 production by human peripheral blood leukocytes. beta-Glucans 22-33 C-X-C motif chemokine ligand 8 Homo sapiens 51-64