PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26405593-0 2015 A novel targeted immunotherapy for CTCL is on its way: Anti-KIR3DL2 mAb IPH4102 is potent and safe in non-clinical studies. iph4102 72-79 TSPY like 2 Homo sapiens 35-39 25361998-2 2014 In this study, we report the development of IPH4102, a humanized monoclonal antibody that targets the immune receptor KIR3DL2, which is widely expressed on CTCL cells but few normal immune cells. iph4102 44-51 TSPY like 2 Homo sapiens 156-160 25361998-3 2014 Potent antitumor properties of IPH4102 were documented in allogeneic human CTCL cells and a mouse model of KIR3DL2(+) disease. iph4102 31-38 TSPY like 2 Homo sapiens 75-79 25361998-8 2014 Together, our results offer preclinical proof of concept for the clinical development of IPH4102 to treat patients with advanced CTCL. iph4102 89-96 TSPY like 2 Homo sapiens 129-133