PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31675511-0 2020 6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase. 6-methyluracil 0-14 acetylcholinesterase (Cartwright blood group) Homo sapiens 117-137 17929660-0 2007 Effect of a tetraalkylammonium derivative of 6-methyluracil from a new class of acetylcholinesterase inhibitors on the endplate potential amplitude in muscles of different function types under high-frequency nerve stimulation. 6-methyluracil 45-59 acetylcholinesterase (Cartwright blood group) Homo sapiens 80-100 31675511-2 2020 Using paraoxon (POX) as a model organophosphate, it was shown that 6-methyluracil derivatives linked with hydroxamic acid are able to reactivate POX-inhibited human acetylcholinesterase (AChE) in vitro. 6-methyluracil 67-81 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-185 31675511-2 2020 Using paraoxon (POX) as a model organophosphate, it was shown that 6-methyluracil derivatives linked with hydroxamic acid are able to reactivate POX-inhibited human acetylcholinesterase (AChE) in vitro. 6-methyluracil 67-81 acetylcholinesterase (Cartwright blood group) Homo sapiens 187-191 26639720-14 2015 In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. 6-methyluracil 52-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 78-82 26639720-0 2015 Macrocyclic derivatives of 6-methyluracil: New ligands of the peripheral anionic site of acetylcholinesterase. 6-methyluracil 27-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 89-109 26639720-13 2015 RESULTS: We described previously a new class of selective mammalian AChE vs. butyrylcholinesterase (BChE) inhibitors based on alkylammonium derivatives of 6-methyluracil of acyclic topology [7]. 6-methyluracil 155-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-72 26929400-0 2016 Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment. 6-methyluracil 82-96 acetylcholinesterase (Cartwright blood group) Homo sapiens 27-47 26929400-1 2016 Inhibition of human AChE (acetylcholinesterase) and BChE (butyrylcholinesterase) by an alkylammonium derivative of 6-methyluracil, C-547, a potential drug for the treatment of MG (myasthenia gravis) was studied. 6-methyluracil 115-129 acetylcholinesterase (Cartwright blood group) Homo sapiens 20-24 26929400-1 2016 Inhibition of human AChE (acetylcholinesterase) and BChE (butyrylcholinesterase) by an alkylammonium derivative of 6-methyluracil, C-547, a potential drug for the treatment of MG (myasthenia gravis) was studied. 6-methyluracil 115-129 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-46 26639720-14 2015 In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. 6-methyluracil 52-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 118-122 26639720-14 2015 In the present study, taking acyclic derivatives of 6-methyluracil as a model AChE inhibitor, we attempted to develop AChE inhibitors that specifically bind to the PAS with weak binding to the active site of AChE. 6-methyluracil 52-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 118-122