PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12574101-7	2003	When exposed to 2 weeks of a salt-free diet (a stress diet stimulating the RAS), blood pressure in ACE 1/3 mice decreased to 92.3+/-2.0 mm Hg, a level significantly lower than that of wild-type control mice.	Salts	29-33	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	99-102	
30571230-7	2018	Females on an HS diet exhibited lower renin-angiotensin system activity (plasma Ang II [angiotensin II], plasma renin activity, and ACE [angiotensin-converting enzyme] activity) compared with males but developed a salt-induced elevation in adrenal aldosterone synthase expression and retained higher aldosterone levels than males on HS.	Salts	214-218	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	137-166	
2221139-0	1990	Effect of angiotensin-converting enzyme inhibitor on salt appetite and thirst of BALB/c mice.	Salts	53-57	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	10-39	
11244026-13	2001	Our results indicate that ACE inhibitors and AT(1) antagonists exert beneficial effects on the heart and kidney in DOCA-salt hypertensive mice independently of their effects on blood pressure.	Salts	120-124	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	26-29	
10076178-1	1999	This study examined whether type 1 angiotensin II receptor (AT1) and angiotensin-converting enzyme (ACE) mRNAs are regulated during dietary salt loading in angiotensinogen gene-knockout (Atg-/-) mice which are genetically deficient in endogenous production of angiotensin II.	Salts	140-144	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	100-103	
10076178-5	1999	Salt loading also enhanced renal cortex ACE mRNA levels in Atg+/+ mice.	Salts	0-4	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	40-43	
10076178-10	1999	Thus, expression of AT1 and ACE is regulated by salt loading in a tissue-specific manner that appears to be mediated, at least partly, by a mechanism other than changes in the circulating or tissue levels of angiotensin peptides.	Salts	48-52	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	28-31	
21597036-5	2011	Treatment with a low-salt diet in combination with an ACE inhibitor increased renin mRNA levels, plasma renin concentrations, and the number of aberrantly localized renin-producing cells.	Salts	21-25	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	54-57	
27988209-2	2017	Here we tested whether renal tubular angiotensin converting enzyme (ACE), the main site of kidney ACE expression, is central to the development of salt sensitivity in this setting.	Salts	147-151	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	68-71	
27988209-7	2017	Thus, in mice with renal injury induced by L-NAME pretreatment, renal tubular epithelial ACE, and not ACE expression by renal endothelium, lung, brain, or plasma, is essential for renal angiotensin II accumulation and salt-sensitive hypertension.	Salts	218-222	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	89-92	
26150439-0	2015	Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme.	Salts	0-4	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	60-89	
26150439-3	2015	Here, we showed that although previously salt-resistant wild-type mice became salt sensitive after the induction of renal injury with the nitric oxide synthase inhibitor Nomega-nitro-l-arginine methyl ester hydrochloride; mice lacking renal angiotensin-converting enzyme, exposed to the same insult, did not become hypertensive when faced with a sodium load.	Salts	78-82	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	241-270	
26150439-5	2015	Thus, this study demonstrates that the presence of renal angiotensin-converting enzyme plays a pivotal role in the development of salt sensitivity in response to renal injury.	Salts	130-134	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	57-86