PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30571230-7 2018 Females on an HS diet exhibited lower renin-angiotensin system activity (plasma Ang II [angiotensin II], plasma renin activity, and ACE [angiotensin-converting enzyme] activity) compared with males but developed a salt-induced elevation in adrenal aldosterone synthase expression and retained higher aldosterone levels than males on HS. Salts 214-218 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 137-166 26150439-5 2015 Thus, this study demonstrates that the presence of renal angiotensin-converting enzyme plays a pivotal role in the development of salt sensitivity in response to renal injury. Salts 130-134 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 57-86 27988209-2 2017 Here we tested whether renal tubular angiotensin converting enzyme (ACE), the main site of kidney ACE expression, is central to the development of salt sensitivity in this setting. Salts 147-151 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 68-71 27988209-7 2017 Thus, in mice with renal injury induced by L-NAME pretreatment, renal tubular epithelial ACE, and not ACE expression by renal endothelium, lung, brain, or plasma, is essential for renal angiotensin II accumulation and salt-sensitive hypertension. Salts 218-222 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 89-92 26150439-0 2015 Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme. Salts 0-4 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 60-89 26150439-3 2015 Here, we showed that although previously salt-resistant wild-type mice became salt sensitive after the induction of renal injury with the nitric oxide synthase inhibitor Nomega-nitro-l-arginine methyl ester hydrochloride; mice lacking renal angiotensin-converting enzyme, exposed to the same insult, did not become hypertensive when faced with a sodium load. Salts 78-82 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 241-270 12574101-7 2003 When exposed to 2 weeks of a salt-free diet (a stress diet stimulating the RAS), blood pressure in ACE 1/3 mice decreased to 92.3+/-2.0 mm Hg, a level significantly lower than that of wild-type control mice. Salts 29-33 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 99-102 21597036-5 2011 Treatment with a low-salt diet in combination with an ACE inhibitor increased renin mRNA levels, plasma renin concentrations, and the number of aberrantly localized renin-producing cells. Salts 21-25 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 54-57 2221139-0 1990 Effect of angiotensin-converting enzyme inhibitor on salt appetite and thirst of BALB/c mice. Salts 53-57 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 10-39 11244026-13 2001 Our results indicate that ACE inhibitors and AT(1) antagonists exert beneficial effects on the heart and kidney in DOCA-salt hypertensive mice independently of their effects on blood pressure. Salts 120-124 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 26-29 10076178-1 1999 This study examined whether type 1 angiotensin II receptor (AT1) and angiotensin-converting enzyme (ACE) mRNAs are regulated during dietary salt loading in angiotensinogen gene-knockout (Atg-/-) mice which are genetically deficient in endogenous production of angiotensin II. Salts 140-144 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 100-103 10076178-5 1999 Salt loading also enhanced renal cortex ACE mRNA levels in Atg+/+ mice. Salts 0-4 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 40-43 10076178-10 1999 Thus, expression of AT1 and ACE is regulated by salt loading in a tissue-specific manner that appears to be mediated, at least partly, by a mechanism other than changes in the circulating or tissue levels of angiotensin peptides. Salts 48-52 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 28-31