PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15567297-1	2005	The activity of the renal peptide transporters PEPT2 and PEPT1 determines-among other factors such as metabolic stability in liver and plasma-the circulatory half-life of penicillins and cephalosporins during therapy.	Cephalosporins	187-201	solute carrier family 15 member 2	Homo sapiens	47-52	
11809991-8	2002	This uptake was competitively inhibited by dipeptides and cephalosporins but not ACE inhibitors, indicating a substrate specificity as described for PEPT2.	Cephalosporins	58-72	solute carrier family 15 member 2	Homo sapiens	149-154	
15282265-3	2004	PEPT2 is also a transporter for peptide-like drugs such as penicillins and cephalosporins.	Cephalosporins	75-89	solute carrier family 15 member 2	Homo sapiens	0-5	
11159208-7	2001	This transport was competitively inhibited by cephalosporins and dipeptides that are reported as PEPT2-carried substrates.	Cephalosporins	46-60	solute carrier family 15 member 2	Homo sapiens	97-102	
9092716-0	1997	Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.	Cephalosporins	23-37	solute carrier family 15 member 2	Homo sapiens	100-106	
9092716-1	1997	The present study was undertaken to investigate the interaction of anionic cephalosporins (cefixime, ceftibuten, and cefdinir) with the renal peptide transporter (PEPT 2) and the intestinal peptide transporter (PEPT 1) using four different experimental model systems.	Cephalosporins	75-89	solute carrier family 15 member 2	Homo sapiens	163-169	
9092716-3	1997	The uptake of the dipeptide Gly-Sar mediated by PEPT 1 or PEPT 2 in these cells was inhibited significantly by the anionic cephalosporins, with the following order of potency: ceftibuten > cefixime > cefdinir.	Cephalosporins	123-137	solute carrier family 15 member 2	Homo sapiens	58-64	
9092716-6	1997	In the second approach, the cloned human PEPT 1 and PEPT 2 were functionally expressed in HeLa cells following which the cells were used to study the interaction of anionic cephalosporins with PEPT 1 and PEPT 2.	Cephalosporins	173-187	solute carrier family 15 member 2	Homo sapiens	52-58	
9092716-7	1997	Again, Gly-Sar uptake mediated by the human PEPT 1 and PEPT 2 in HeLa cells was found to be inhibited by the anionic cephalosporins with the same order potency as in Caco-2 and SKPT cells.	Cephalosporins	117-131	solute carrier family 15 member 2	Homo sapiens	55-61	
9092716-13	1997	It is concluded that anionic cephalosporins interact with the peptide transporters expressed in the intestine (PEPT 1) as well as in the kidney (PEPT 2).	Cephalosporins	29-43	solute carrier family 15 member 2	Homo sapiens	145-151	
7592745-4	1995	The substrate recognition pattern of PEPT 1 and PEPT 2 was studied with cefadroxil (a cephalosporin) and cyclacillin (a penicillin) as model substrates for the peptide transporters constitutively expressed in Caco-2 cells (PEPT 1) and SKPT cells (PEPT 2).	Cephalosporins	86-99	solute carrier family 15 member 2	Homo sapiens	48-54