PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35175332-5	2022	The antibiotic susceptibility of E. coli cells harboring E169A and N173A substituted CTX-M-15 were enhanced by ~ >32 fold for penicillins and ~ 4-32 fold for cephalosporins, in comparison to CTX-M-15.	Cephalosporins	158-172	hypothetical protein	Escherichia coli	85-93	
33013784-6	2020	Phylogroups B1 and B2 were dominant in the E. coli population, while phylogroup A was dominant in isolates resistant to third-generation cephalosporins, which harbored the extended-spectrum beta-lactamase (ESBL) encoding genes bla CTX-M-15 and bla CTX-M-27 in half of the cases.	Cephalosporins	137-151	hypothetical protein	Escherichia coli	231-239	
31832181-6	2019	Method: In this study, the cephalosporin-resistant E. coli isolate NCTC 1553 (E. coli CTXM-15) was analysed by qRT-PCR (quantitative Reverse Transcriptase -Polymerase Chain Reaction) for the expression of virulence factors after treatment with Cysticlean .	Cephalosporins	27-40	hypothetical protein	Escherichia coli	86-93	
29760961-10	2018	The high-level multidrug resistance of uropathogens to third generation cephalosporins including other antibiotics used in this study is strongly associated with carriage of ESBLs, predominantly CTX-M-15, as well as CTX-X-M-14, OXA-10, and VEB-1.	Cephalosporins	72-86	hypothetical protein	Escherichia coli	195-203	
31824726-5	2019	AMR bacteria were found in 62.7% of the samples, the majority thereof were resistant to third-generation cephalosporins due to the production of extended-spectrum beta-lactamases (ESBLs) including CTX-M-1, which is widespread in livestock, and CTX-M-15, which is the most common ESBL variant worldwide.	Cephalosporins	105-119	hypothetical protein	Escherichia coli	244-252	
26317445-1	2016	CTX-M-15 is a chief contributor for expanded-spectrum cephalosporin and monobactam resistance in India, complicating treatment options.	Cephalosporins	54-67	hypothetical protein	Escherichia coli	0-8	
31804991-13	2018	CONCLUSIONS: This study shows the predominance of CTX-M-15 among cephalosporin-resistant E. coli and K. pneumoniae in Lebanese hospitals and highlights the direct relationship between the use of antibiotics and the emergence of resistance in bacteria.	Cephalosporins	65-78	hypothetical protein	Escherichia coli	50-58	
28756026-20	2017	CONCLUSIONS: This study shows the predominance of CTX-M-15 among cephalosporin-resistant E. coli and Klebsiella spp.	Cephalosporins	65-78	hypothetical protein	Escherichia coli	50-58	
23284886-10	2012	Our findings demonstrate that bla(CTX-M-15) is the most prevalent ESBL and we report a larger than previously reported prevalence of ampC genes among Enterobacteriaceae responsible for resistance to third-generation cephalosporins.	Cephalosporins	216-230	hypothetical protein	Escherichia coli	34-42	
21393166-7	2011	Two different promoters were found to transcribe bla(CTX-M-15), resulting in different levels of cephalosporin resistance.	Cephalosporins	97-110	hypothetical protein	Escherichia coli	53-61