PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17827719-7 2007 However, the eNOS inhibitor N(G)-monomethyl-L-arginine effectively inhibited tube formation, but partially blocked proliferation and migration as well as ERK phosphorylation, without altering Akt and eNOS activation, revealing that the eNOS/NO pathway is partially involved in ERK1/2 activation. omega-N-Methylarginine 28-54 nitric oxide synthase 3 Homo sapiens 13-17 11132600-13 2000 acetylcholine (average increase: + 554 +/- 371%), nitroprusside or L-NMMA infusion were found across the eNOS genotypes, neither for endothelium-dependent or endothelium-independent vasodilation, nor for basal NO production and release. omega-N-Methylarginine 67-73 nitric oxide synthase 3 Homo sapiens 105-109 16824503-9 2006 L-NMMA and glibenclamide abrogated the effects of nicorandil on ventricular function, coronary blood flow volume, area of no-reflow, necrosis area and cNOS activity, but not iNOS activity. omega-N-Methylarginine 0-6 nitric oxide synthase 3 Homo sapiens 151-155 16102116-8 2005 This effect was significantly reduced by the addition of the K+ channel blocker iberiotoxin (100 nmol L(-1)), eNOS inhibitor L-NMMA (300 micromol L(-1)), or the MEK inhibitor PD 98059 (20 micromol L(-1)). omega-N-Methylarginine 125-131 nitric oxide synthase 3 Homo sapiens 110-114 16102116-11 2005 An increase of +101% MAPK phosphorylation was induced by HGF, which was blocked, if the cells were treated with L-NMMA (n = 20; P < 0.05), whereas HGF-induced phosphorylation of the eNOS was not affected by MEK inhibition. omega-N-Methylarginine 112-118 nitric oxide synthase 3 Homo sapiens 185-189 12359981-2 2002 OBJECTIVE: To investigate functional differences between the various genotypes with respect to basal nitric oxide (NO) production, we estimated the response to endothelial NO synthase (ecNOS) inhibition by infusion of increasing doses of N(G)-monomethyl-L-arginine (L-NMMA) into the brachial artery during venous occlusion plethysmography. omega-N-Methylarginine 238-264 nitric oxide synthase 3 Homo sapiens 185-190 11862754-2 2002 Free intracellular L-NMMA and ADMA, but not SDMA, are inhibitors of all three isoforms of nitric oxide synthases (nNOS, eNOS and iNOS). omega-N-Methylarginine 19-25 nitric oxide synthase 3 Homo sapiens 120-124 10471612-7 1999 In contrast, L-NMMA infusion that inhibited endothelial NOS, as evidenced by an increase in blood pressure and a decrease in heart rate, had only a barely detectable effect on exhaled NO (-11 +/- 4% from baseline). omega-N-Methylarginine 13-19 nitric oxide synthase 3 Homo sapiens 44-59 10747895-5 2000 N(omega)-Methyl-l-arginine, an inhibitor of eNOS that blocks NO production but not its NADPH oxidase activity, did not prevent TNFalpha up-regulation. omega-N-Methylarginine 0-26 nitric oxide synthase 3 Homo sapiens 44-48 18516617-4 2008 Combined endothelial nitric oxide synthase (eNOS) and cyclooxygenase (COX) inhibition was achieved by an intradermal injection (10 microl) of the eNOS inhibitor, L(omega)-monomethyl L-arginine (L-NMMA, 10 mM) and the COX inhibitor, diclofenac (10 mM); saline was injected as a control. omega-N-Methylarginine 194-200 nitric oxide synthase 3 Homo sapiens 9-42 9689061-5 1998 No inhibition is observed after addition of L-arginine, NG-hydroxy-L-arginine, L-thiocitrulline, and L-NG-monomethyl arginine to activated eNOS. omega-N-Methylarginine 101-125 nitric oxide synthase 3 Homo sapiens 139-143 9202399-3 1997 NO synthase (NOS) inhibitors with affinity for the inducible (iNOS) and the constitutive (cNOS) isoform such as N(G)-monomethyl-L-arginine (L-NMMA) and S-methyl-L-thiocitrulline (SMLT) dose-dependently blocked the inhibitory action of IFN-gamma on GHRH-stimulated GH secretion, and partially reversed the inhibitory effect on basal prolactin (PRL) release. omega-N-Methylarginine 112-138 nitric oxide synthase 3 Homo sapiens 90-94 9202399-3 1997 NO synthase (NOS) inhibitors with affinity for the inducible (iNOS) and the constitutive (cNOS) isoform such as N(G)-monomethyl-L-arginine (L-NMMA) and S-methyl-L-thiocitrulline (SMLT) dose-dependently blocked the inhibitory action of IFN-gamma on GHRH-stimulated GH secretion, and partially reversed the inhibitory effect on basal prolactin (PRL) release. omega-N-Methylarginine 140-146 nitric oxide synthase 3 Homo sapiens 90-94 28904082-6 2017 The methylarginine and eNOS inhibitor L-NMMA was higher in early and late postmenopausal women compared to premenopausal and early and late perimenopausal women (all P < 0.001), and was inversely correlated with FMD (r = -0.30, P = 0.001). omega-N-Methylarginine 38-44 nitric oxide synthase 3 Homo sapiens 23-27 21566204-7 2012 Results suggest that endothelial nitric oxide synthase-mediated formation of nitric oxide (NO) from L-NMMA in doses >3.2 micromol/min and continuous PE-induced alpha-adrenergic stimulation resulting in release of very small amounts of NO from L-NMMA contribute to the observed L-NMMA-induced increase in vein size. omega-N-Methylarginine 100-106 nitric oxide synthase 3 Homo sapiens 21-54 21566204-7 2012 Results suggest that endothelial nitric oxide synthase-mediated formation of nitric oxide (NO) from L-NMMA in doses >3.2 micromol/min and continuous PE-induced alpha-adrenergic stimulation resulting in release of very small amounts of NO from L-NMMA contribute to the observed L-NMMA-induced increase in vein size. omega-N-Methylarginine 246-252 nitric oxide synthase 3 Homo sapiens 21-54 21566204-7 2012 Results suggest that endothelial nitric oxide synthase-mediated formation of nitric oxide (NO) from L-NMMA in doses >3.2 micromol/min and continuous PE-induced alpha-adrenergic stimulation resulting in release of very small amounts of NO from L-NMMA contribute to the observed L-NMMA-induced increase in vein size. omega-N-Methylarginine 246-252 nitric oxide synthase 3 Homo sapiens 21-54 18242654-9 2008 Co-infusion of the eNOS inhibitor N(G)-monomethyl-L-arginine (L-NMMA) changed the effect of aldosterone on renal hemodynamics. omega-N-Methylarginine 34-60 nitric oxide synthase 3 Homo sapiens 19-23 18242654-9 2008 Co-infusion of the eNOS inhibitor N(G)-monomethyl-L-arginine (L-NMMA) changed the effect of aldosterone on renal hemodynamics. omega-N-Methylarginine 62-68 nitric oxide synthase 3 Homo sapiens 19-23 18792879-1 2008 Asymmetric dimethylarginine (ADMA) and NG-monomethyl- L-arginine ( L-NMMA) are important endogenous endothelial nitric oxide synthase (eNOS) inhibitors. omega-N-Methylarginine 39-64 nitric oxide synthase 3 Homo sapiens 100-133 18792879-1 2008 Asymmetric dimethylarginine (ADMA) and NG-monomethyl- L-arginine ( L-NMMA) are important endogenous endothelial nitric oxide synthase (eNOS) inhibitors. omega-N-Methylarginine 67-73 nitric oxide synthase 3 Homo sapiens 100-133