PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26409001-0	2015	Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.	Trehalose	88-97	huntingtin	Homo sapiens	120-130	
32649191-3	2020	Here we report hyperbranched polyglycerol dendrimer terminated with anti-amyloidogenic small molecules such as gallate, tyrosine and trehalose and their potential in inhibiting lysozyme/huntingtin protein aggregation under intra/extracellular space.	Trehalose	133-142	huntingtin	Homo sapiens	186-196	
26957541-2	2016	Cell treatment with trehalose could decrease cytosolic aggregates of potentially pathogenic proteins, including mutant huntingtin, alpha-synuclein, and phosphorylated tau that are associated with neurodegenerative diseases.	Trehalose	20-29	huntingtin	Homo sapiens	119-129	
28356891-2	2017	Trehalose induces abundant autophagy in cultured cells and also reduces the rate of aggregation of the huntingtin protein in the animal model of Huntington disease, a chronic neurological disease in humans.	Trehalose	0-9	huntingtin	Homo sapiens	103-113	
26409001-6	2015	Interestingly, the combined treatment of EHNs and trehalose leads to more degradation of mutant huntingtin protein aggregates than that obtained with single treatment of either nanorods or trehalose.	Trehalose	50-59	huntingtin	Homo sapiens	96-106	
24587280-8	2014	Treatment with trehalose counteracts the increase in ROS, ubiquitinated proteins, huntingtin and activated caspase-3 levels induced by epoxomicin, and also increases the LC3 levels more in HD fibroblast than controls.	Trehalose	15-24	huntingtin	Homo sapiens	82-92	
17182613-0	2007	Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.	Trehalose	0-9	huntingtin	Homo sapiens	92-102	
17182613-4	2007	Trehalose-induced autophagy enhanced the clearance of autophagy substrates like mutant huntingtin and the A30P and A53T mutants of alpha-synuclein, associated with Huntington disease (HD) and Parkinson disease (PD), respectively.	Trehalose	0-9	huntingtin	Homo sapiens	87-97