PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35463818-7	2022	Protein levels of NFE2L2 showed a 50% reduction in aged rats compared to young rats (P<0.001), which was restored by trehalose intervention.	Trehalose	117-126	NFE2 like bZIP transcription factor 2	Rattus norvegicus	18-24	
32641951-0	2019	Trehalose Neuroprotective Effects on the Substantia Nigra Dopaminergic Cells by Activating Autophagy and Non-canonical Nrf2 Pathways.	Trehalose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	119-123	
31195231-0	2019	Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury.	Trehalose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	39-43	
33226392-0	2020	Involvement of Nrf2 and mitochondrial apoptotic signaling in trehalose protection against cadmium-induced kidney injury.	Trehalose	61-70	NFE2 like bZIP transcription factor 2	Rattus norvegicus	15-19	
32641951-6	2019	In addition, the antioxidant effects of trehalose were assessed by analyzing the levels of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and also glutathione reductase (GR), glutathione peroxidase (GPx) and Catalase (CAT) enzymes.	Trehalose	40-49	NFE2 like bZIP transcription factor 2	Rattus norvegicus	91-134	
32641951-11	2019	In the current study, trehalose simultaneously protects substantia nigra dopaminergic cells by activating both non-canonical p62/SQSTM1-Keap1-Nrf2 and autophagy pathways.	Trehalose	22-31	NFE2 like bZIP transcription factor 2	Rattus norvegicus	142-146	
30599315-0	2019	Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis.	Trehalose	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	62-66	
29140578-0	2018	Alleviation of cadmium-induced oxidative stress by trehalose via inhibiting the Nrf2-Keap1 signaling pathway in primary rat proximal tubular cells.	Trehalose	51-60	NFE2 like bZIP transcription factor 2	Rattus norvegicus	80-84	
29140578-2	2018	Here, we aimed to investigate whether trehalose (Tre) protects primary rat proximal tubular (rPT) cells against cadmium (Cd)-induced oxidative stress via Nrf2 antioxidant pathway.	Trehalose	38-47	NFE2 like bZIP transcription factor 2	Rattus norvegicus	154-158